Investigating the potential mechanisms and therapeutic targets of inflammatory cytokines in post-stroke depression

Y Zhang, Y Yang, H Li, Q Feng, W Ge, X Xu - Molecular Neurobiology, 2024 - Springer
Post-stroke depression (PSD) affects approximately one-third of stroke survivors, severely
impacting general recovery and quality of life. Despite extensive studies, the exact …

[HTML][HTML] Neural substrates of poststroke depression: current opinions and methodology trends

C Pan, G Li, W Sun, J Miao, X Qiu, Y Lan… - Frontiers in …, 2022 - frontiersin.org
Poststroke depression (PSD), affecting about one-third of stroke survivors, exerts significant
impact on patients' functional outcome and mortality. Great efforts have been made since the …

[HTML][HTML] Post-stroke depression increases disability more than 15% in ischemic stroke survivors: a case-control study

S Paolucci, M Iosa, P Coiro, V Venturiero… - Frontiers in …, 2019 - frontiersin.org
We performed a retrospective, case-control study in consecutive ischemic stroke patients
admitted to our stroke rehabilitation unit. Patients were matched for severity of neurological …

[HTML][HTML] Predictors of post-stroke depression: Validation of established risk factors and introduction of a dynamic perspective in two longitudinal studies

S Ladwig, K Werheid, M Südmeyer, M Volz - Frontiers in Psychiatry, 2023 - frontiersin.org
Introduction Cerebral insults lead in many cases not only to cognitive impairment but also to
disturbed emotionality. After stroke, one in three survivors develops a depression which …

Pyruvate kinase M2 (PKM2) improve symptoms of post‐ischemic stroke depression by activating VEGF to mediate the MAPK/ERK pathway

Y Feng, X Li, J Wang, X Huang, L Meng… - Brain and …, 2022 - Wiley Online Library
Purpose To evaluate and identify the effects and explore the mechanisms of pyruvate kinase
M2 (PKM2) on stroke‐induced post stroke depression (PSD). Methods Rats were separated …

[HTML][HTML] Global cerebral ischemia-induced depression accompanies alteration of neuronal excitability in the infralimbic cortex layer 2/3 pyramidal neurons

DC Jang, S Choi, G Chung, SK Kim - Experimental Neurobiology, 2023 - ncbi.nlm.nih.gov
Cerebral ischemia can lead to a range of sequelae, including depression. The pathogenesis
of depression involves neuronal change of the medial prefrontal cortex (mPFC). However …

Too much and too little: antidepressant treatment in stroke survivors during the first year

K Weheid, M Volz, S Ladwig… - Journal of Integrative …, 2022 - clok.uclan.ac.uk
Background: Post-stroke depression (PSD) is the most frequent mental illness after stroke,
affecting about 30% of stroke survivors and hampering rehabilitation outcome. While current …

[图书][B] Madness in Experience and History: Merleau-Ponty's Phenomenology and Foucault's Archaeology

HL Venable - 2021 - taylorfrancis.com
Madness in Experience and History brings together experience and history to show their
impact on madness or mental illness. Drawing on the writings of two twentieth-century …

[图书][B] Stroke Survivors' and Informal Caregivers' Perceptions of Depressive Symptoms After Stroke: A Mixed-Methods Sequential Explanatory Study

TLB Trotter - 2023 - search.proquest.com
Background: Poststroke depression (PSD) is a frequently occurring complication of stroke
that affects up to 30% of all stroke survivors in the first 24 months after stroke. PSD has been …

Mechanisms and Perspectives of Post-Stroke Depression: Neuroanatomical Substrates, Incentive Motivation, and Emotional Processing

JL Koob - 2024 - kups.ub.uni-koeln.de
Post-stroke depression (PSD) is a prevalent affective condition after a stroke, which can
impair functional and motor rehabilitation. The present dissertation and the included studies …