[HTML][HTML] RNA modifications: importance in immune cell biology and related diseases
L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …
including generation, transportation, function, and metabolization, they act as critical …
[HTML][HTML] Epigenetic modification of m6A regulator proteins in cancer
Abstract Divergent N6-methyladenosine (m6A) modifications are dynamic and reversible
posttranscriptional RNA modifications that are mediated by m6A regulators or m6A RNA …
posttranscriptional RNA modifications that are mediated by m6A regulators or m6A RNA …
[HTML][HTML] Mutual regulation between N6-methyladenosine (m6A) modification and circular RNAs in cancer: impacts on therapeutic resistance
H Lin, Y Wang, P Wang, F Long, T Wang - Molecular cancer, 2022 - Springer
The resistance of tumor cells to therapy severely impairs the efficacy of treatment, leading to
recurrence and metastasis of various cancers. Clarifying the underlying mechanisms of …
recurrence and metastasis of various cancers. Clarifying the underlying mechanisms of …
N6-methyladenosine-mediated gene regulation and therapeutic implications
Abstract N6-methyladenosine (m 6 A) RNA methylation is the most abundant form of mRNA
modification in eukaryotes and is at the front line of biological and biomedical research. This …
modification in eukaryotes and is at the front line of biological and biomedical research. This …
[HTML][HTML] m6A methylation: a process reshaping the tumour immune microenvironment and regulating immune evasion
X Cao, Q Geng, D Fan, Q Wang, X Wang, M Zhang… - Molecular cancer, 2023 - Springer
Abstract N6-methyladenosine (m6A) methylation is the most universal internal modification
in eukaryotic mRNA. With elaborate functions executed by m6A writers, erasers, and …
in eukaryotic mRNA. With elaborate functions executed by m6A writers, erasers, and …
[HTML][HTML] The chromatin-associated RNAs in gene regulation and cancer
J Tang, X Wang, D Xiao, S Liu, Y Tao - Molecular Cancer, 2023 - Springer
Eukaryotic genomes are prevalently transcribed into many types of RNAs that translate into
proteins or execute gene regulatory functions. Many RNAs associate with chromatin directly …
proteins or execute gene regulatory functions. Many RNAs associate with chromatin directly …
[HTML][HTML] METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression
W Wei, ZY Zhang, B Shi, Y Cai, HS Zhang… - Journal of Experimental …, 2023 - Springer
Background Glycolysis is the key hallmark of cancer and maintains malignant tumor
initiation and progression. The role of N6-methyladenosine (m6A) modification in glycolysis …
initiation and progression. The role of N6-methyladenosine (m6A) modification in glycolysis …
M6AREG: m6A-centered regulation of disease development and drug response
As the most prevalent internal modification in eukaryotic RNAs, N 6-methyladenosine (m6A)
has been discovered to play an essential role in cellular proliferation, metabolic …
has been discovered to play an essential role in cellular proliferation, metabolic …
Novel insights into the interaction between N6‐methyladenosine methylation and noncoding RNAs in musculoskeletal disorders
J Han, H Kong, X Wang, X Zhang - Cell Proliferation, 2022 - Wiley Online Library
Background Musculoskeletal disorder (MSD) are a class of inflammatory and degener‐ative
diseases, but the precise molecular mechanisms are still poorly understood. Noncoding …
diseases, but the precise molecular mechanisms are still poorly understood. Noncoding …
[HTML][HTML] The emerging importance role of m6A modification in liver disease
S Wang, S Gao, W Ye, Y Li, J Luan, X Lv - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract N6-methyladenosine (m6A) modification, as one of the most common types of inner
RNA modification in eukaryotes, plays a multifunctional role in normal and abnormal …
RNA modification in eukaryotes, plays a multifunctional role in normal and abnormal …