Lung cancer is a prevalent malignant tumor and a leading cause of cancer-related fatalities
globally. However, current treatments all have limitations. Therefore, there is an urgent need …

Myocardial infarction (MI) is one of the most prevalent types of cardiovascular disease.
During MI, myocardial cells become ischemic and necrotic due to inadequate blood …

Background Small molecules have emerged as valuable tools to modulate cellular
homeostasis and the changes associated with aging. In particular, the phytochemical …

Vimentin has been reported to play diverse roles in cell processes such as spreading,
migration, cell–matrix adhesion, and fibrotic transformation. Here, we assess how vimentin …

Abstract Background and Purpose Nicorandil, a selective opener of potassium channels,
used to treat angina, has drawn attention for its potential in mitigating lung injury, positioning …

Objective To investigate whether tricyclic decylbenzoxazole (TDB) regulates liver cancer cell
proliferation and apoptosis through p300-mediated FOXO acetylation. Methods Sequencing …

Osteoarthritis is a chronic degenerative disease based on the degeneration and loss of
articular cartilage. Inflammation and aging play an important role in the destruction of the …

Silicosis is an occupational respiratory disease caused by long-term inhalation of high
concentrations of free silica particles. Studies suggest that oxidative stress is a crucial …

After a stromal injury in the cornea, the release of growth factors and pro-inflammatory
cytokines typically results in the activation of quiescent keratocytes toward migratory …

Background: Small molecules have emerged as valuable tools to modulate cellular
homeostasis and the changes associated with aging. In particular, the phytochemical …