The classic definition of precocious sexual maturation is the development of secondary
sexual characteristics before 8 years of age in girls and before 9 years of age in boys. It is …

Abstract The Committee of Central Precocious Puberty of Korean Pediatrics and
Adolescents of the Korean Society of Pediatric Endocrinology has newly developed …

Context Transgender adolescents can receive gonadotropin-releasing hormone analogues
(GnRH) and gender-affirming hormone therapy (GAHT), but little is known about effects on …

Background/Aims Central precocious puberty (CPP) is due to premature activation of the
hypothalamic-pituitary-gonadal axis. It predominantly affects girls. CPP leads to lower final …

Precocious puberty (PP) means the appearance of secondary sexual characters before the
age of eight years in girls and nine years in boys. Puberty is indicated in girls by the …

Objectives To study total growth, rate of bone maturation, and menarche after
discontinuation of Gonadotropin releasing hormone agonist (GnRHa) treatment for central …

Body composition in sexual precocity : Current Opinion in Endocrinology, Diabetes and
Obesity Body composition in sexual precocity : Current Opinion in Endocrinology, Diabetes …

Central precocious puberty (CPP) refers to early activation of the hypothalamic–pituitary–
gonadal (HPG) axis and is manifested by breast development in girls or testicular …

The typical timing of male puberty begins between 9 and 14 years old, at an average age of
11.6 Æ 0.9 years. 1 Luteinizing hormone (LH), measured via an ultrasensitive assay, acts as …

GnRHas remain as the only fully efficacious therapy for CPP and effectively suppress
pubertal hormones in other situations. The use of GnRHa therapy in gender incongruent …