Alzheimer's disease (AD) is an age-related progressive neurodegenerative disorder that
leads to cognitive impairment and memory loss. Emerging evidence suggests that …

Despite the air quality has been generally improved in recent years, ambient fine particulate
matter (PM2. 5), a major contributor to air pollution, remains one of the major threats to …

Mitophagy induction upon mitochondrial stress is critical for maintaining mitochondrial
homeostasis and cellular function. Here, we found that Mst1/2 (Stk3/4), key regulators of the …

Subcellular mitochondria serve as sensors for energy metabolism and redox balance, and
the dynamic regulation of functional and dysfunctional mitochondria plays a crucial role in …

Palmatine, a natural alkaloid found in various plants, has been reported to have diverse
pharmacological and biological effects, including anti-inflammatory, antioxidant, and …

Background Cardiovascular disease (CVD) remains the leading cause of morbidity and
mortality worldwide, imposing an enormous economic burden on individuals and human …

Mitochondria are double-membrane organelles within eukaryotic cells that act as cellular
power houses owing to their ability to efficiently generate the ATP required to sustain normal …

Objective To explore the potential mechanism of mitophagy mediated by PINK1 in the
pathogenesis of AM. Method The study compared PINK1, Parkin, OPTIN, P62, and NDP52 …

Cadmium (Cd) is a common environmental pollutant, while selenium (Se) can ameliorate
heavy metal toxicity. Consequently, this study aimed to investigate the protective effects of …

Abstract Background and Purpose Mitochondrial dysfunction contributes to the
pathogenesis and maintenance of chemotherapyinduced peripheral neuropathy (CIPN), a …