[HTML][HTML] Role of omega-3 fatty acids in cardiovascular disease: the debate continues

SCR Sherratt, P Libby, MJ Budoff, DL Bhatt… - Current atherosclerosis …, 2023 - Springer
Abstract Purpose of Review The omega-3 fatty acids (n3-FAs), eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), have recently undergone testing for their ability to reduce …

Omega-3 and cardiovascular prevention–Is this still a choice?

M Ruscica, CR Sirtori, S Carugo, PC Calder… - Pharmacological …, 2022 - Elsevier
There is currently growing attention being paid to the role of elevated triglycerides (TGs) as
important mediators of residual atherosclerotic cardiovascular disease (ASCVD) risk. This …

Clinical Trial Design for Triglyceride-Rich Lipoprotein-Lowering Therapies: JACC Focus Seminar 3/3

WA Malick, O Waksman, R Do, W Koenig… - Journal of the American …, 2023 - jacc.org
Triglyceride-rich lipoproteins (TRLs) are a source of residual risk in patients with
atherosclerotic cardiovascular disease, and are indirectly correlated with triglyceride (TG) …

Severe hypertriglyceridemia: Existing and emerging therapies

WA Malick, R Do, RS Rosenson - Pharmacology & Therapeutics, 2023 - Elsevier
Severe hypertriglyceridemia (sHTG), defined as a triglyceride (TG) concentration≥ 500
mg/dL (≥ 5.7 mmol/L) is an important risk factor for acute pancreatitis. Although lifestyle …

[HTML][HTML] VLDL receptor gene therapy for reducing atherogenic lipoproteins

RM Krauss, JT Lu, JJ Higgins, CM Clary… - Molecular Metabolism, 2023 - Elsevier
Over the past 40 years, there has been considerable research into the management and
treatment of atherogenic lipid disorders. Although the majority of treatments and …

[HTML][HTML] A critical review of icosapent ethyl in cardiovascular risk reduction

J Huston, H Schaffner, A Cox, A Sperry… - American Journal of …, 2023 - Springer
Icosapent ethyl (IPE) was the first fish oil product the US Food and Drug Administration
(FDA) approved to reduce the risk of atherosclerotic cardiovascular disease (ASCVD) in …

[HTML][HTML] Frontiers and hotspots evolution in anti-inflammatory studies for coronary heart disease: A bibliometric analysis of 1990–2022

J Zhang, C Ji, X Zhai, H Tong, J Hu - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Background: Coronary heart disease (CHD) is characterized by forming of arterial plaques
composed mainly of lipids, calcium, and inflammatory cells. These plaques narrow the …

[HTML][HTML] The anti-aggregative potential of resolvin E1 on human platelets

P Szymańska, B Luzak, K Miłowska, J Golański - Molecules, 2023 - mdpi.com
Resolvin E1 is a metabolite of eicosapentaenoic acid (EPA) which is one of the omega-3
polyunsaturated fatty acids (omega-3 PUFAs). The antiplatelet properties of omega-3 PUFAs …

Do patients benefit from omega-3 fatty acids?

SCR Sherratt, RP Mason, P Libby… - Cardiovascular …, 2023 - academic.oup.com
Abstract Omega-3 fatty acids (O3FAs) possess beneficial properties for cardiovascular (CV)
health and elevated O3FA levels are associated with lower incident risk for CV disease …

[HTML][HTML] Saturated fatty acids negatively affect musculoskeletal tissues in vitro and in vivo

RT Lin, B Osipov, D Steffen, M Chamberlin, SJ Pathak… - Matrix Biology Plus, 2024 - Elsevier
Fish oils rank among the world's most popular nutritional supplements and are purported to
have numerous health benefits. Previous work suggested that fish oils increase collagen …