The role of bacterial lipid diversity and membrane properties in modulating antimicrobial peptide activity and drug resistance

TH Lee, V Hofferek, F Separovic, GE Reid… - Current opinion in …, 2019 - Elsevier
This review provides an analysis of the role that membrane composition and structure plays
in the resistance of microorganisms to antimicrobial peptides (AMPs). We describe the …

Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR–STAT3 signalling

X Gao, X Xia, F Li, M Zhang, H Zhou, X Wu, J Zhong… - Nature cell …, 2021 - nature.com
Activated EGFR signalling drives tumorigenicity in 50% of glioblastoma (GBM). However,
EGFR-targeting therapy has proven ineffective in treating patients with GBM, indicating that …

Refractometric imaging and biodetection empowered by nanophotonics

S Sun, L Wu, Z Geng, PP Shum, X Ma… - Laser & Photonics …, 2023 - Wiley Online Library
Advancing clinical and nonclinical diagnostic technologies is particularly crucial for
improved preparedness for the next pandemic and other global healthcare challenges. To …

Solvent-assisted preparation of supported lipid bilayers

AR Ferhan, BK Yoon, S Park, TN Sut, H Chin… - Nature protocols, 2019 - nature.com
The supported lipid bilayer (SLB) platform is a popular cell membrane mimic that is utilized
in the chemical, biological, materials science, and medical fields. To date, SLB preparation …

Gold Nanoparticle Enabled Localized Surface Plasmon Resonance on Unique Gold Nanomushroom Structures for On‐Chip CRISPR‐Cas13a Sensing

J Waitkus, Y Chang, L Liu… - Advanced materials …, 2023 - Wiley Online Library
A novel localized surface plasmon resonance (LSPR) system based on the coupling of gold
nanomushrooms (AuNMs) and gold nanoparticles (AuNPs) is developed to enable a …

Protein aggregation and neurodegenerative disease: structural outlook for the novel therapeutics

S Arar, MA Haque, R Kayed - Proteins: Structure, Function, and …, 2023 - Wiley Online Library
Before the controversial approval of humanized monoclonal antibody lecanemab, which
binds to the soluble amyloid‐β protofibrils, all the treatments available earlier, for …

Extreme long-lifetime self-assembled monolayer for air-stable molecular junctions

N Chen, S Li, P Zhao, R Liu, Y Xie, JL Lin… - Science …, 2023 - science.org
The molecular electronic devices based on self-assembled monolayer (SAM) on metal
surfaces demonstrate novel electronic functions for device minimization yet are unable to …

Label-free imaging of single proteins and binding kinetics using total internal reflection-based evanescent scattering microscopy

P Zhang, R Wang, Z Wan, X Zhou, G Ma… - Analytical …, 2022 - ACS Publications
Single-molecule detection can push beyond ensemble averages and reveal the statistical
distributions of molecular properties. Measuring the binding kinetics of single proteins also …

Effect of cholesterol on the fluidity of supported lipid bilayers

Y Zhang, Q Li, M Dong, X Han - Colloids and Surfaces B: Biointerfaces, 2020 - Elsevier
The lateral mobility serves as a key function of the cell membrane and can be regulated by
the cholesterol. Here supported lipid bilayers were used to quantitatively analyse the …

Artificial cell membrane platforms by solvent-assisted lipid bilayer (SALB) formation

H Tae, C Yang, NJ Cho - Accounts of Materials Research, 2022 - ACS Publications
Conspectus Supported lipid bilayers (SLBs) are artificial cell membrane platforms that
recapitulate key aspects of lipid membrane architecture on material surfaces. Their …