The extraordinary success of mRNA vaccines against coronavirus disease 2019 (COVID-19)
has renewed interest in mRNA as a means of delivering therapeutic proteins. Early clinical …

Interest in intranasal (IN) administration as a non-invasive route for drug delivery continues
to grow rapidly. The nasal mucosa offers numerous benefits as a target issue for drug …

1. Introduction study nasal absorption of drugs. This area of drug delivery received
additional attention with a timely The most desirable and convenient method of drug seminar …

Nasal drug administration has been used as an alternative route for the systemic availability
of drugs restricted to intravenous administration. This is due to the large surface area …

Many drugs are not being effectively and efficiently delivered using conventional drug
delivery approach to brain or central nervous system (CNS) due to its complexity. The brain …

The blood brain barrier (BBB) represents one of the strictest barriers of in vivo therapeutic
drug delivery. The barrier is defined by restricted exchange of hydrophilic compounds, small …

The intranasal (IN-) administration of substances is attracting attention from scientists as well
as pharmaceutical companies. The effects are surprisingly fast and specific. The present …

Intranasal insulin delivery has been widely investigated as an alternative to subcutaneous
injection for the treatment of diabetes. The pharmacokinetic profile of intranasal insulin is …

The transport of 145I-radiolabelled latex nanoparticles across the nasal mucosa of rats was
studied using a range of particle sizes and surface coatings. Translocation of the particles …

Accumulating research demonstrates the potential of intranasal delivery of
psychopharmacological agents to treat a range of psychiatric disorders and symptoms. It is …