Phosphatidylserine (PS) and phosphatidylethanolamine (PE) are metabolically related
membrane aminophospholipids. In mammalian cells, PS is required for targeting and …

The glycerophospholipids phosphatidylcholine (PC) and phosphatidylethanolamine (PE)
account for greater than 50% of the total phospholipid species in eukaryotic membranes and …

Mitochondrial dysfunction is implicated in neurodegenerative, cardiovascular, and metabolic
disorders, but the role of phospholipids, particularly the nonbilayer-forming lipid …

The cell cycle is central to understanding fundamental biology of Leishmania, a group of
human‐infective protozoan parasites. Leishmania have two main life cycle morphologies …

Mitochondria exert critical functions in cellular lipid metabolism and promote the synthesis of
major constituents of cellular membranes, such as phosphatidylethanolamine (PE) and …

Mitochondria play a key role in cellular signalling, metabolism and energetics. Proper
architecture and remodelling of the inner mitochondrial membrane are essential for efficient …

Lipid metabolism is of crucial importance for pathogens. Lipids serve as cellular building
blocks, signalling molecules, energy stores, posttranslational modifiers, and pathogenesis …

In many eukaryotes, phospholipids (PLs) and sphingolipids (SLs) are abundant membrane
components and reservoirs for important signaling molecules. In Leishmania, the …

Mutations in genes involved in lipid metabolism have increasingly been associated with
various subtypes of hereditary spastic paraplegia, a highly heterogeneous group of …

This article provides a historical account of the discovery, chemistry, and biochemistry of two
ubiquitous phosphoglycerolipids, phosphatidylserine (PS) and phosphatidylethanolamine …