Edaravone alleviates methotrexate-induced testicular injury in rats: Implications on inflammation, steroidogenesis, and Akt/p53 signaling

EHM Hassanein, WR Mohamed, RM Hussein… - International …, 2023 - Elsevier
Edaravone (ED) is a neuroprotective drug with beneficial effects against several disorders
due to its prominent antioxidant activity. However, its effect against methotrexate (MTX) …

Vitamin D Status and Psoriatic Arthritis: Association with the Risk for Sacroiliitis and Influence on the Retention Rate of Methotrexate Monotherapy and First Biological …

C Rotondo, FP Cantatore, D Cici, F Erroi… - International Journal of …, 2023 - mdpi.com
A growing body of evidence on the importance of vitamin D in immune modulation has
increased the interest in its possible impact on the course of rheumatological diseases. The …

Therapeutic effect of stem cells on male infertility in a rat model: histological, molecular, biochemical, and functional study

SS Mohammed, MF Mansour… - Stem Cells …, 2021 - Wiley Online Library
Methotrexate (MTX) is a folic acid antagonist, widely used as a chemotherapeutic and
immunosuppressive drug, but it is toxic to reproductive systems. In recent years, the era of …

[HTML][HTML] Histopathological examination of the mucosal effects of obstetric gel on vaginal wound healing in an incision-inflicted rat model

P Kırıcı, S Kaplan, BA Turk, E Annac - Cureus, 2021 - ncbi.nlm.nih.gov
Materials and methods Twenty-one female Wistar albino rats were divided into three groups,
comprising seven animals per group. The first group (group 1) was the control group, the …

Effects of Vitamin D on doxorubucin-induced lung injury and TRPM2 immunoreactivity in rats

A Yalçın, A Türk, H Aydın, E Yılmaz, İS Çelik… - Journal of Surgery …, 2020 - dergipark.org.tr
Aim: Although doxorubicin (DOX) is a commonly used chemotherapeutic agent, it causes
significant toxic side effects on many organs. This study aims to investigate the effects of …

Exhibit Anti-Inflammatory, Antioxidant, and Anti-Androgen Effect in Rat Model of Experimental Polycystic Ovarian Syndrome

GOPKN Mavralc, ZEU Korund, EAS Kaplanf - 2024 - karger.com
Objective: Chronic inflammation is considered to be of key importance in the pathogenesis
of polycystic ovarian syndrome (PCOS). Ganoderma lucidum polysaccharide (GLP) and …

Metotreksatın Neden Olduğu Testis Hasarında Quercetin'in Etkilerinin Histolojik Olarak Incelenmesi

B Baran - 2023 - search.proquest.com
METOTREKSATIN NEDEN OLDUĞU TESTİS HASARINDA QUERCETİN’İN ETKİLERİNİN
HİSTOLOJİK OLARAK İNCELENMESİ BURCU BARAN ORCI Page 1 1 TC DOKUZ EYLÜL …

Possible effects of some anaesthetic agents in rat hepatotoxicity: Histological and biochemical study

E Annaç, Ö Uludag, Z Doğan - Journal of Experimental and Clinical …, 2022 - dergipark.org.tr
Selectively steroidal neuromuscular blocking agents, such as rocuronium, are required to
maintain surgical procedures. It is a sugammadex γ-cyclodextrin-derived drug that …