Skeletal muscle atrophy: From mechanisms to treatments

L Yin, N Li, W Jia, N Wang, M Liang, X Yang… - Pharmacological …, 2021 - Elsevier
Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic
homeostasis, and thermogenesis. It makes up approximately 40% of the total body weight …

[HTML][HTML] Sarcopenia in the older adult with cancer

GR Williams, RF Dunne, S Giri… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
The term sarcopenia, derived from the Greek words sarx for flesh and penia for loss, was first
introduced by Rosenberg 1 in 1989 to describe the loss of muscle mass that accompanies …

[HTML][HTML] Prognostic value of sarcopenia in adults with solid tumours: a meta-analysis and systematic review

SS Shachar, GR Williams, HB Muss… - European journal of …, 2016 - Elsevier
Background Body composition plays an important role in predicting treatment outcomes in
adults with cancer. Using existing computed tomographic (CT) cross-sectional imaging and …

Japan Society of Hepatology guidelines for sarcopenia in liver disease: Recommendation from the working group for creation of sarcopenia assessment criteria

H Nishikawa, M Shiraki, A Hiramatsu… - Hepatology …, 2016 - Wiley Online Library
Sarcopenia is defined by muscle loss and muscle dysfunction. Sarcopenia is classified into
primary and secondary types, based on the cause. Primary sarcopenia is mainly aging …

[HTML][HTML] Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinoma

N Fujiwara, H Nakagawa, Y Kudo, R Tateishi… - Journal of …, 2015 - Elsevier
Background & Aims Obesity defined by body mass index (BMI) significantly increases the
risk of hepatocellular carcinoma (HCC). In contrast, not only obesity but also underweight is …

Sarcopenia and postoperative complication risk in gastrointestinal surgical oncology: a meta-analysis

C Simonsen, P de Heer, ED Bjerre, C Suetta… - Annals of …, 2018 - journals.lww.com
Objective: The aim of the study was to evaluate sarcopenia as a predictor of postoperative
risk of major and total complications after surgery for gastrointestinal cancer. Background …

Computed tomography‐defined low skeletal muscle index and density in cancer patients: observations from a systematic review

J McGovern, RD Dolan, PG Horgan… - Journal of cachexia …, 2021 - Wiley Online Library
Background Computed tomography (CT) analysis of body composition has garnered interest
as a potential prognostic tool in those with cancer. A range of pre‐defined thresholds …

[HTML][HTML] Forcing the vicious circle: sarcopenia increases toxicity, decreases response to chemotherapy and worsens with chemotherapy

F Bozzetti - Annals of oncology, 2017 - Elsevier
Sarcopenia has recently emerged as a new condition that, independently from malnutrition,
may adversely affect the prognosis of cancer patients. Purpose of this narrative review is to …

Computed tomography-defined muscle and fat wasting are associated with cancer clinical outcomes

SMR Kazemi-Bajestani, VC Mazurak… - Seminars in cell & …, 2016 - Elsevier
Cancer cachexia (ie, skeletal muscle wasting with or without fat loss) relates to several
adverse outcomes. Computed tomography (CT) cross-sectional images serve as an efficient …

[HTML][HTML] Reference values for skeletal muscle mass–current concepts and methodological considerations

CO Walowski, W Braun, MJ Maisch, B Jensen, S Peine… - Nutrients, 2020 - mdpi.com
Assessment of a low skeletal muscle mass (SM) is important for diagnosis of ageing and
disease-associated sarcopenia and is hindered by heterogeneous methods and …