The H-NS (heat-stable nucleoid structuring) protein affects both nucleoid compaction and
global gene regulation. H-NS appears to act primarily as a silencer of AT-rich genetic …

Every organism across the tree of life compacts and organizes its genome with architectural
chromatin proteins. While eukaryotes and archaea express histone proteins, the …

Bacterial H-NS forms nucleoprotein filaments that spread on DNA and bridge distant DNA
sites. H-NS filaments co-localize with sites of Rho-dependent termination in Escherichia coli …

Bacteria frequently need to adapt to altered environmental conditions. Adaptation requires
changes in gene expression, often mediated by global regulators of transcription. The …

Horizontal gene transfer plays an important role in the evolution of bacterial species,
conferring new genetic traits on the recipient bacterium that extend its range of phenotypes …

In enterobacteria, AT-rich horizontally acquired genes, including virulence genes, are
silenced through the actions of at least three nucleoid-associated proteins (NAPs): H-NS …

Nucleoid-associated proteins typically are abundant, low-molecular-mass polypeptides that
bind DNA and alter its shape and its ability to participate in transactions such as …

Highlights•Similarities in the DNA binding properties of H-NS and RNA polymerase.•
Interactions between H-NS and RNA polymerase throughout the transcription cycle.•H-NS …

Transcriptional regulation for genome expression determines growth and adaptation of
single-cell bacteria that are directly exposed to environment. The transcriptional apparatus …

Escherichia coli K-12 possesses two versions of Trk/Ktr/HKT-type potassium ion (K+)
transporters, TrkG and TrkH. The current paradigm is that TrkG and TrkH have largely …