Plasmacytoid dendritic cells in the setting of myeloid neoplasms: diagnostic guide to challenging pathologic presentations

S El Hussein, W Wang - British Journal of Haematology, 2023 - Wiley Online Library
In this article, we describe three broad pathologic presentations of plasmacytoid dendritic
cells (pDCs) that may be encountered in clinical practice, in which an association between …

[HTML][HTML] Plasmacytoid dendritic cell neoplasms

YJ Lee, Y Kim, SH Park, JC Jo - Blood research, 2023 - ncbi.nlm.nih.gov
Plasmacytoid dendritic cells (pDCs) are type I interferon-producing cells that modulate
immune responses. There are two types of pDC neoplasms: 1) mature pDC proliferation …

Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1-mutated acute myeloid leukemia

W Xiao, A Chan, MR Waarts, T Mishra… - Blood, The Journal …, 2021 - ashpublications.org
Plasmacytoid dendritic cells (pDCs) are the principal natural type I interferon–producing
dendritic cells. Neoplastic expansion of pDCs and pDC precursors leads to blastic …

Dendritic cell leukemia: a review

NJ Tsagarakis, G Paterakis - Current Oncology Reports, 2020 - Springer
Abstract Purpose of Review The purpose of this review was to summarize the clinical,
diagnostic, and therapeutic features of blastic plasmacytoid dendritic cell neoplasm …

Prognostic role of DOK family adapters in acute myeloid leukemia

L Zhang, R Li, K Hu, Y Dai, Y Pang, Y Jiao, Y Liu… - Cancer Gene …, 2019 - nature.com
Acute myeloid leukemia (AML) is a genetically and clinically heterogeneous disease. Gene
mutational and expressional profile can aid the identification of different prognostic …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) arising in the setting of polycythemia vera (PV): An illustration of the emerging role of flow cytometry analysis in …

S El Hussein, M Yabe, W Wang, N Pemmaraju… - …, 2022 - Wiley Online Library
This report highlights the value of flow cytometry analysis, particularly in the setting of
myeloproliferative neoplasms showing features of progression, as neoplastic plasmacytoid …

[HTML][HTML] E-cadherin expression and blunted interferon response in blastic plasmacytoid dendritic cell neoplasm

L Lorenzi, S Lonardi, D Vairo… - The American Journal …, 2021 - journals.lww.com
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive neoplasm derived
from plasmacytoid dendritic cells (pDCs). In this study, we investigated by …

A simple cytofluorimetric score may optimize testing for biallelic CEBPA mutations in patients with acute myeloid leukemia

R Marcolin, F Guolo, P Minetto, M Clavio, L Manconi… - Leukemia Research, 2019 - Elsevier
Acute myeloid leukemia with biallelic mutation of CEBPA (CEBPA-dm AML) is a distinct
good prognosis entity recognized by WHO 2016 classification. However, testing for CEBPA …

Prognostic significance of microRNA-99a in acute myeloid leukemia patients undergoing allogeneic hematopoietic stem cell transplantation

Z Cheng, L Zhou, K Hu, Y Dai, Y Pang… - Bone Marrow …, 2018 - nature.com
Overexpression of microRNA-99a (miR-99a) have been associated with adverse prognosis
in acute myeloid leukemia (AML). Nevertheless, whether it also predicts poor outcome in …

A blastic plasmacytoid dendritic cell neoplasm-like immunophenotype is negatively associated with CEBPA bZIP mutation and predicts unfavorable prognosis in acute …

J Song, W Li, Y Bai, P Zhou, J Niu, X Niu, Y Liu… - Annals of …, 2024 - Springer
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive myeloid
malignancy which characteristically expresses an atypical phenotype including CD123+ …