Autoimmunity eventuates when the immune system attacks self-molecules as a result of the
breakdown in immune tolerance. Targeting autoimmune diseases via immunomodulation …

Vitiligo is an autoimmune skin disorder defined by the destruction of functional epidermal
melanocytes. It is a multifactorial and polygenic disorder caused due to oxidative stress …

Background Pro-inflammatory/anti-inflammatory cytokine imbalance in cerebrospinal fluid or
plasma of schizophrenia (SCZ) and bipolar disorder (BD) patients has been documented …

Background The antigen processing 1 (TAP1) and proteasome 20S subunit beta 9 (PSMB9)
genes are associated with strong susceptibility to many autoimmune diseases. Here, we …

Immunity and cytokines serve crucial roles in cutaneous melanoma. The present study
investigated whether a variable number tandem repeat (VNTR) polymorphism of interleukin …

Vitiligo is a hypomelanotic skin disease and considered to be of autoimmune origin due to
breaching of immunological self-tolerance, resulting in inappropriate immune responses …

Introduction Vitiligo is a depigmenting disorder resulting from loss of functional melanocytes
in the skin. Variety of inflammatory mediators participate in the regulation of melanogenesis …

Introduction The IL-1 receptor antagonist (IL-1Ra or IL-1RN) is a member of the IL-1
superfamily that functions as a competitive antagonist of the cell surface IL-1 receptor …

Background Interleukin-1 receptor antagonist (IL1RN) variable number tandem repeats
(VNTRs) are not fully understood in Type 1 diabetes mellitus (T1DM). It may affect IL1RN …

Background Vitiligo is an acquired hypomelanotic autoimmune disorder characterized by
depigmented macules on the skin. Oxidative stress acts as an initial trigger and …