Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …

Head and neck cancer

MD Mody, JW Rocco, SS Yom, RI Haddad, NF Saba - The Lancet, 2021 - thelancet.com
Head and neck cancer is the seventh most common type of cancer worldwide and comprise
of a diverse group of tumours affecting the upper aerodigestive tract. Although many different …

Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment

AT Ruffin, H Li, L Vujanovic, DP Zandberg… - Nature Reviews …, 2023 - nature.com
Targeted immunotherapy has improved patient survival in head and neck squamous cell
carcinoma (HNSCC), but less than 20% of patients produce a durable response to these …

Head and neck cancers, version 2.2020, NCCN clinical practice guidelines in oncology

DG Pfister, S Spencer, D Adelstein, D Adkins… - Journal of the National …, 2020 - jnccn.org
Treatment is complex for patients with head and neck (H&N) cancers with specific site of
disease, stage, and pathologic findings guiding treatment decision-making. Treatment …

Tumor angiogenesis: causes, consequences, challenges and opportunities

R Lugano, M Ramachandran, A Dimberg - Cellular and Molecular Life …, 2020 - Springer
Tumor vascularization occurs through several distinct biological processes, which not only
vary between tumor type and anatomic location, but also occur simultaneously within the …

IPDfromKM: reconstruct individual patient data from published Kaplan-Meier survival curves

N Liu, Y Zhou, JJ Lee - BMC medical research methodology, 2021 - Springer
Background When applying secondary analysis on published survival data, it is critical to
obtain each patient's raw data, because the individual patient data (IPD) approach has been …

Oral mucositis: the hidden side of cancer therapy

C Pulito, A Cristaudo, CL Porta, S Zapperi… - Journal of experimental …, 2020 - Springer
Inflammation response of epithelial mucosa to chemo-radiotherapy cytotoxic effects leads to
mucositis, a painful side effect of antineoplastic treatments. About 40% of the patients treated …

Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and …

JP Machiels, CR Leemans, W Golusinski… - Annals of …, 2020 - annalsofoncology.org
Squamous cell carcinoma of the head and neck (SCCHN) arises from epithelial cells and
occurs in the oral cavity, pharynx and larynx. Nasopharyngeal carcinoma (NPC) is a disease …

Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non …

ML Gillison, AM Trotti, J Harris, A Eisbruch, PM Harari… - The Lancet, 2019 - thelancet.com
Background Patients with human papillomavirus (HPV)-positive oropharyngeal squamous
cell carcinoma have high survival when treated with radiotherapy plus cisplatin. Whether …