Curcumin can improve spinal cord injury by inhibiting DNA methylation

Y Zhou, Y Zhang, BOA Botchway, X Wang… - Molecular and Cellular …, 2024 - Springer
Spinal cord injury (SCI) is a serious central nervous system disease. Traumatic SCI often
causes persistent neurological deficits below the injury level. Epigenetic changes occur after …

POLYDATIN AMELIORATES TRAUMATIC BRAIN INJURY–INDUCED SECONDARY BRAIN INJURY BY INHIBITING NLRP3-INDUCED NEUROINFLAMMATION …

Q Li, P Zhao, Y Wen, Z Zou, X Qin, H Tan, J Gong… - Shock, 2023 - journals.lww.com
Traumatic brain injury (TBI) is a kind of disease with high morbidity, mortality, and disability,
and its pathogenesis is still unclear. Research shows that nucleotide-binding …

[HTML][HTML] Repeated ethanol exposure and withdrawal alters ACE2 expression in discrete brain regions: Implications for SARS-CoV-2 infection

N Balasubramanian, TD James, SG Pushpavathi… - bioRxiv, 2022 - ncbi.nlm.nih.gov
Emerging evidence suggests that people with alcohol use disorders are at higher risk for
SARS-CoV-2. SARS-CoV-2 engages angiotensin-converting enzyme 2 (ACE2) and …

Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer's disease

S Pierson, KL Fiock, R Wang, N Balasubramanian… - bioRxiv, 2022 - biorxiv.org
Protein aggregation in brainstem nuclei is thought to occur in the early stages of Alzheimer's
disease (AD), but its specific role in driving prodromal symptoms and disease progression is …

Behavioral dysregulation and monoaminergic deficits precede memory impairments in human tau-overexpressing (htau) mice

KM Khan, GP Selvakumar, N Balasubramanian… - bioRxiv, 2022 - biorxiv.org
Alzheimer's disease (AD) poses an ever-increasing public health concern as the population
ages, affecting more than 6 million Americans. AD patients present with mood and sleep …

Polydatin ameliorates TBI induced secondary brain injury by inhibiting NLRP3-induced neuroinflammation associated with SOD2 acetylation.

Q Li, P Zhao, Y Wen, Z Zou, X Qin, H Tan… - Shock (Augusta …, 2022 - europepmc.org
Traumatic brain injury (TBI) is a kind of disease with high morbidity, mortality and disability,
and its pathogenesis is still unclear. Research shows that nucleotide-binding …

[PDF][PDF] Neuroinflammation Mediated Epigenetic Reprogramming: Implications and Impact in Neurodegenerative Diseases

RC Bekal, SD Pereira, K Satyamoorthy - researchgate.net
There are multiple mechanisms involved in epigenetic regulation that coordinate to regulate
switching on and switch off genes, in both normal physiological functions and diseased …

[引用][C] Polydatin Inhibits NLRP3-Mediated Neuroinflammation by Restore SOD2 Deacetylation Activity Following Traumatic Brain Injury

Q Li, X Qin, Z Zou, H Tan, J Gong, Q Wu, C Zheng…