Anti-angiogenic therapy: current challenges and future perspectives

F Lopes-Coelho, F Martins, SA Pereira… - International journal of …, 2021 - mdpi.com
Anti-angiogenic therapy is an old method to fight cancer that aims to abolish the nutrient and
oxygen supply to the tumor cells through the decrease of the vascular network and the …

Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy

M Gao, F Yu, C Lv, J Choo, L Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …

[PDF][PDF] Tumor microenvironment: extracellular matrix alterations influence tumor progression

S Brassart-Pasco, S Brézillon, B Brassart… - Frontiers in …, 2020 - frontiersin.org
The tumor microenvironment (TME) is composed of various cell types embedded in an
altered extracellular matrix (ECM). ECM not only serves as a support for tumor cell but also …

Biomedical applications of plant extract-synthesized silver nanoparticles

S Simon, NRS Sibuyi, AO Fadaka, S Meyer, J Josephs… - Biomedicines, 2022 - mdpi.com
Silver nanoparticles (AgNPs) have attracted a lot of interest directed towards biomedical
applications due in part to their outstanding anti-microbial activities. However, there have …

A systematic review of glioblastoma-targeted therapies in phases II, III, IV clinical trials

E Cruz Da Silva, MC Mercier, N Etienne-Selloum… - Cancers, 2021 - mdpi.com
Simple Summary This review describes in a very detailed and exhaustive approach the
literature of these last 20 years on glioblastoma targeted therapies in Phases II-IV of 257 …

A comprehensive review on the anti-cancer effects of oleuropein

S Rishmawi, F Haddad, G Dokmak, R Karaman - Life, 2022 - mdpi.com
In Mediterranean cuisine and culture, olive oil and olive fruits play a significant role. Many
people believe that those who consume olive oil and its fruit live longer and have a …

The role of extracellular matrix proteins in breast cancer

A Lepucki, K Orlińska, A Mielczarek-Palacz… - Journal of Clinical …, 2022 - mdpi.com
The extracellular matrix is a structure composed of many molecules, including fibrillar (types
I, II, III, V, XI, XXIV, XXVII) and non-fibrillar collagens (mainly basement membrane collagens …

The impact of matrix metalloproteinase-9 on the sequential steps of the metastatic process

G Barillari - International journal of molecular sciences, 2020 - mdpi.com
In industrialized countries, cancer is the second leading cause of death after cardiovascular
disease. Most cancer patients die because of metastases, which consist of the self …

Targeting angiogenesis and lymphangiogenesis in kidney disease

K Tanabe, J Wada, Y Sato - Nature Reviews Nephrology, 2020 - nature.com
The kidney is permeated by a highly complex vascular system with glomerular and
peritubular capillary networks that are essential for maintaining the normal functions of …

The functional role of extracellular matrix proteins in cancer

NV Popova, M Jücker - Cancers, 2022 - mdpi.com
Simple Summary Extracellular matrix is a three-dimensional network of macromolecules that
provide structural and biochemical support to surrounding cells. Extracellular matrix plays a …