Carcinogenic N-nitrosamine contamination in certain drugs has recently caused great
concern and the attention of regulatory agencies. These carcinogens—widely detectable in …

Nitrate is a natural constituent of the human diet and an approved food additive. It can be
partially converted to nitrogen monoxide, which induces vasodilation and thereby decreases …

Glioblastoma multiforme (GBM) is a grade IV brain tumor characterized by a heterogeneous
population of cells that are highly infiltrative, angiogenic and resistant to chemotherapy. The …

Red meat is associated with increased risk of colorectal cancer and increases the
endogenous formation of N-nitrosocompounds (NOC). To investigate the genotoxic effects of …

Nitrosamines occur widespread in food, drinking water, cosmetics, as well as tobacco smoke
and can arise endogenously. More recently, nitrosamines have been detected as impurities …

Colorectal cancer (CRC) is one of the major tumor entities worldwide, with an increasing
incidence in younger people. CRC formation is causally linked to various genetic, life-style …

Recent improvements in the ability to detect chemically modified bases in DNA have
revealed that not only does the genetic material incur damage by foreign chemicals, but that …

Red or processed meat, but not white meat or fish, is associated with colorectal cancer. The
endogenous formation of nitroso compounds is a possible explanation, as red or processed …

Epidemiological and mechanistic studies suggest that processed and red meat consumption
and tobacco smoking are associated with colorectal cancer (CRC) risk. Several classes of …

Azaserine (1) is a natural product and nonproteinogenic amino acid containing a diazo
group. Here we report the biosynthetic gene cluster for 1 from Glycomyces harbinensis. We …