Glucocorticoid‐induced hyperglycemia (糖皮质激素诱导的高血糖)

A Perez, S Jansen‐Chaparro, I Saigi… - Journal of …, 2014 - Wiley Online Library
摘要糖皮质激素诱导的高血糖是一个常见的医疗问题, 它使患者频繁至急诊室就诊,
并延长入院及住院时间, 除此之外还有众所周知的高血糖导致死亡率增加的问题. 然而 …

Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids

D Czock, F Keller, FM Rasche, U Häussler - Clinical pharmacokinetics, 2005 - Springer
Glucocorticoids have pleiotropic effects that are used to treat diverse diseases such as
asthma, rheumatoid arthritis, systemic lupus erythematosus and acute kidney transplant …

Glucocorticoid-induced hyperglycemia

JN Clore, L Thurby-Hay - Endocrine practice, 2009 - Elsevier
Objective To review the current literature on glucocorticoid-induced hyperglycemia and
provide a strategy for its treatment. Methods We undertook an electronic (MEDLINE) and a …

Sex differences in pharmacokinetics and pharmacodynamics

M Gandhi, F Aweeka, RM Greenblatt… - Annu. Rev. Pharmacol …, 2004 - annualreviews.org
The importance of reviewing and studying sex-based differences in pharmacologic
parameters is demonstrated by the increasing data on gender variation in drug efficacy and …

Why ethnic minority groups are under‐represented in clinical trials: a review of the literature

M Hussain‐Gambles, K Atkin… - Health & social care in …, 2004 - Wiley Online Library
Randomised controlled trials (RCTs) are considered to be the gold standard in evaluating
medical interventions; however, people from ethnic minorities are frequently under …

Diversity of mechanism-based pharmacodynamic models

DE Mager, E Wyska, WJ Jusko - Drug metabolism and disposition, 2003 - ASPET
Pharmacodynamics is the study of the time course of pharmacological effects of drugs. The
field of pharmacodynamic modeling has made many advances, due in part to the relatively …

Sex and the kidneys: current understanding and research opportunities

CN Bairey Merz, LM Dember, JR Ingelfinger… - Nature Reviews …, 2019 - nature.com
Concerns regarding sex differences are increasingly pertinent in scientific and societal
arenas. Although biological sex and socio-cultural gender are increasingly recognized as …

Glucocorticoid-induced hyperglycemia

S Kwon, KL Hermayer, K Hermayer - The American journal of the medical …, 2013 - Elsevier
Objectives Provide treatment guidelines for glucocorticoid-induced hyperglycemia and to
understand the clinical implications of glucocorticoid-induced hyperglycemia. Methods The …

Chronopharmacology of glucocorticoids

ML Scherholz, N Schlesinger, IP Androulakis - Advanced drug delivery …, 2019 - Elsevier
Glucocorticoids influence a wide array of metabolic, anti-inflammatory, immunosuppressive,
and cognitive signaling processes, playing an important role in homeostasis and …

Demographics, assessment and management of pain in the elderly

MP Davis, M Srivastava - Drugs & aging, 2003 - Springer
The prevalence of pain increases with each decade of life. Pain in the elderly is distinctly
different from pain experienced by younger individuals. Cancer is a leading cause of pain; …