CCR4 as a therapeutic target for cancer immunotherapy

O Yoshie - Cancers, 2021 - mdpi.com
Simple Summary CCR4 is a chemokine receptor selectively expressed on normal T cell
subsets such as type 2 helper T cells, skin-homing T cells and regulatory T cells, and on skin …

Infectious Agents as Potential Drivers of α‐Synucleinopathies

M Linard, A Ravier, L Mougué, I Grgurina… - Movement …, 2022 - Wiley Online Library
Abstract α‐synucleinopathies, encompassing Parkinson's disease, dementia with Lewy
bodies, and multiple system atrophy, are devastating neurodegenerative diseases for which …

NK cells and monocytes modulate primary HTLV-1 infection

R Moles, S Sarkis, V Galli, M Omsland, M Artesi… - PLoS …, 2022 - journals.plos.org
We investigated the impact of monocytes, NK cells, and CD8+ T-cells in primary HTLV-1
infection by depleting cell subsets and exposing macaques to either HTLV-1 wild type …

Selective APC-targeting of a novel Fc-fusion multi-immunodominant recombinant protein (tTax-tEnv: mFcγ2a) for HTLV-1 vaccine development

M Shafifar, SH Mozhgani, KR Pashabayg, A Mosavat… - Life Sciences, 2022 - Elsevier
Aims HTLV-1 causes two life-threatening diseases: adult T-cell leukaemia/lymphoma and
HTLV-1-associated myelopathy/tropical spastic paraparesis. Due to the lack of proper …

[HTML][HTML] Brazilian protocol for sexually transmitted infections 2020: human T-cell lymphotropic virus (HTLV) infection

C Rosadas, C Brites, D Arakaki-Sanchez… - Revista da Sociedade …, 2021 - SciELO Brasil
This article addresses the Human T-lymphotropic virus (HTLV). This subject comprises the
Clinical Protocol and Therapeutic Guidelines for Comprehensive Care for People with …

Multicenter, randomized, double-blind, placebo-controlled phase 3 study of mogamulizumab with open-label extension study in a minimum number of patients with …

T Sato, M Nagai, O Watanabe, T Misu… - Journal of …, 2024 - Springer
Human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) is a chronic neurodegenerative disease characterized by …

[HTML][HTML] Protocolo Brasileiro para Infecções Sexualmente Transmissíveis 2020: infecção pelo vírus linfotrópico de células T humanas (HTLV)

C Rosadas, C Brites, D Arakaki-Sánchez… - … e Serviços de Saúde, 2021 - SciELO Brasil
O artigo aborda a infecção pelo vírus linfotrópico de células T humanas (human T
lymphotropic virus, HTLV), tema contemplado no Protocolo Clínico e Diretrizes Terapêuticas …

Mechanism of secondary glaucoma development in HTLV-1 uveitis

Y Zong, K Kamoi, N Ando, H Kurozumi-Karube… - Frontiers in …, 2022 - frontiersin.org
Human T-cell lymphotropic virus type 1 (HTLV-1) was the first retrovirus identified as the
causative agent of human diseases, such as adult T-cell leukemia, HTLV-1-associated …

Safety of intraocular anti-VEGF antibody treatment under in vitro HTLV-1 infection

Y Zong, K Kamoi, H Kurozumi-Karube, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction HTLV-1 (human T-cell lymphotropic virus type 1) is a retrovirus that infects
approximately 20 million people worldwide. Many diseases are caused by this virus …

Tuning Rex rules HTLV-1 pathogenesis

K Nakano, T Watanabe - Frontiers in Immunology, 2022 - frontiersin.org
HTLV-1 is an oncovirus causing ATL and other inflammatory diseases such as HAM/TSP
and HU in about 5% of infected individuals. It is also known that HTLV-1-infected cells …