Tauopathies are a group of neurodegenerative diseases characterized by the
hyperphosphorylation and deposition of tau proteins in the brain. In Alzheimer's disease …

Familial Alzheimer's disease (FAD) is a complex neurodegenerative disorder for which there
are no therapeutics to date. Several mutations in presenilin 1 (PSEN 1), which is the catalytic …

Trinucleotide repeat disorders comprise~ 20 severe, inherited, human neuromuscular and
neurodegenerative disorders, which result from an abnormal expansion of repetitive …

Neurodegenerative diseases (ND) share common molecular/cellular mechanisms that
contribute to their progression and pathogenesis. In this sense, we are here proposing new …

There is increasing evidence that dysfunction of essential metal (Cu, Zn, Fe, Mn)
homeostasis can lead to the appearance of several NDs. Other neurotoxic environmental …

Transcriptomic responses to neurotransmitters contribute to the complex processes driving
memory and addiction. Advances in both measurement methods and experimental models …

With the appreciation that behavior represents the integration and complexity of the nervous
system, neurobehavioral phenotyping and assessment has seen a renaissance over the last …

The chemoradiotherapy technique is widely applied in the treatment of cancerous disease.
Nowadays, nanoparticles are used in drug delivery and it is essential to confirm the …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most prevalent age-
related neurodegenerative diseases, and currently no effective clinical treatments exist for …

Parkinson's disease (PD) is the second most common neurodegenerative disorder in
worldwide and remains a therapeutic challenge due to the low efficacy of current treatments …