The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment

AH Ashok, TR Marques, S Jauhar, MM Nour… - Molecular …, 2017 - nature.com
Bipolar affective disorder is a common neuropsychiatric disorder. Although its
neurobiological underpinnings are incompletely understood, the dopamine hypothesis has …

[HTML][HTML] Studying human neurological disorders using induced pluripotent stem cells: from 2D monolayer to 3D organoid and blood brain barrier models

S Logan, T Arzua, SG Canfield… - Comprehensive …, 2019 - ncbi.nlm.nih.gov
Neurological disorders have emerged as a predominant healthcare concern in recent years
due to their severe consequences on quality of life and prevalence throughout the world …

[HTML][HTML] The economic burden of bipolar I disorder in the United States in 2015

M Cloutier, M Greene, A Guerin, M Touya… - Journal of affective …, 2018 - Elsevier
Background The current societal costs of bipolar I disorder (BDI) have not been
comprehensively characterized in the United States, as previous studies are based on data …

Trastorno Bipolar. Consideraciones clínicas y epidemiológicas

O Martínez Hernández, O Montalván Martínez… - Revista médica …, 2019 - scielo.sld.cu
El trastorno bipolar es un trastorno crónico y recurrente que se caracteriza por fluctuaciones
patológicas del estado del ánimo. Las fases de la enfermedad incluyen episodios …

The role of DNA methylation in the pathophysiology and treatment of bipolar disorder

GR Fries, Q Li, B McAlpin, T Rein, C Walss-Bass… - Neuroscience & …, 2016 - Elsevier
Bipolar disorder (BD) is a multifactorial illness thought to result from an interaction between
genetic susceptibility and environmental stimuli. Epigenetic mechanisms, including DNA …

Bipolar disorder and diabetes mellitus: evidence for disease-modifying effects and treatment implications

EF Charles, CG Lambert, B Kerner - International journal of bipolar …, 2016 - Springer
Background Bipolar disorder refers to a group of chronic psychiatric disorders of mood and
energy levels. While dramatic psychiatric symptoms dominate the acute phase of the …

Do atypical antipsychotics have antisuicidal effects? A hypothesis-generating overview

M Pompili, RJ Baldessarini, A Forte, D Erbuto… - International journal of …, 2016 - mdpi.com
Modern antipsychotic drugs are employed increasingly in the treatment of mood disorders
as well as psychoses, stimulating interest in their possible contributions to altering suicidal …

Pharmacological effects and therapeutic potential of natural compounds in neuropsychiatric disorders: An update

P Asgharian, C Quispe, J Herrera-Bravo… - Frontiers in …, 2022 - frontiersin.org
Neuropsychiatric diseases are a group of disorders that cause significant morbidity and
disability. The symptoms of psychiatric disorders include anxiety, depression, eating …

Cannabis and mood disorders

AM Lucatch, AS Coles, KP Hill, TP George - Current addiction reports, 2018 - Springer
Abstract Purpose of Review The present review will provide an overview of the
neurobiology, epidemiology, clinical impact, and treatment of cannabis use disorder (CUD) …

[HTML][HTML] Clinically relevant response and remission outcomes in cariprazine-treated patients with bipolar I disorder

W Earley, S Durgam, K Lu, A Ruth, G Németh… - Journal of Affective …, 2018 - Elsevier
Background Rates of response and remission are measures that endorse the clinical
significance of treatment. Cariprazine is FDA approved for the acute treatment of …