The deregulation of the MYC family of oncogenes, including c-MYC, MYCN and MYCL
occurs in many types of cancers, and is frequently associated with a poor prognosis. The …

The role of proliferation-associated protein 2G4 (PA2G4), alternatively known as ErbB3-
binding protein 1 (EBP1), in cancer has become apparent over the past 20 years. PA2G4 …

To achieve the very high oncoprotein levels required to drive the malignant state cancer
cells utilise the ubiquitin proteasome system to upregulate transcription factor levels. Here …

Simple Summary Neuroblastoma is a pediatric tumor originating from the sympathetic
nervous system responsible for 10–15% of all childhood cancer deaths. Half of all …

An increasing number of studies have found that long non‐coding RNA (lncRNA) play
important roles in driving the progression of nasopharyngeal carcinoma (NPC). Our …

Histone deacetylase (HDAC) inhibitors are effective in MYCN-driven cancers, because of a
unique need for HDAC recruitment by the MYCN oncogenic signal. However, HDAC …

Neuroblastoma (NB) is one of the most frequently occurring neurogenic extracranial solid
cancers in childhood and infancy. Over the years, many pieces of evidence suggested that …

The overexpression of the ecotropic viral integration site-1 gene (EVI1/MECOM) marks the
most lethal acute myeloid leukemia (AML) subgroup carrying chromosome 3q26 …

Informative and realistic mouse models of high-risk neuroblastoma are central to
understanding mechanisms of tumour initiation, progression, and metastasis. They also play …

During COVID-19 lockdowns, online learning activities had to be developed for the
Undergraduate and Masters by Coursework Bioinformatics students at RMIT University …