The medical community recognizes sex-related differences in pathophysiology and
cardiovascular disease outcomes (CVD), culminating with heart failure. In general, pre …

Sex differences in cardiovascular disease (CVD) are often recognized from experimental
and clinical studies examining the prevalence, manifestations, and response to therapies …

Aims Recent evidence supports non-class cardioprotective effects of metoprolol against
neutrophil-mediated ischemia-reperfusion injury during exacerbated inflammation. Whether …

Introduction Sex hormones may play an important role in age-related cardiac remodeling.
However, their impact on cardiac structure and function in females of advanced age still …

Cardiovascular diseases (CVDs) are the leading cause of mortality and disability among
both males and females. The risk of cardiovascular diseases is heightened by the presence …

In 2016, an estimated 486,000 individuals sustained burn injuries requiring medical
attention. Severe burn injuries lead to a persistent, hyperinflammatory response that may …

Several studies have demonstrated estrogen's cardioprotective abilities in decreasing the
fibrotic response of cardiac fibroblasts (CFs). However, the majority of these studies are not …

Myocardial infarction (MI) can induce heart failure with reduced ejection fraction (HFrEF).
Systemic circulation is of importance to interact with MI-induced HFrEF. Hence, we studied …

β-blockers have been widely utilized as a part of acute myocardial infarction (AMI) treatment
for the past 40 years. Patients receiving β-adrenergic blockers for an extended period …

Background: If menopause is really independent risk factor for cardiovascular disease is still
under debate. We studied if ovariectomy in the model of insulin resistance causes …