Calcific aortic valve disease (CAVD) is a highly prevalent condition that comprises a disease
continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodelling …

Abstract Chronic Kidney Disease (CKD) is linked to a rising prevalence of morbidity and
mortality primarily from cardiovascular complications and is considered a high or very high …

Cardiovascular diseases (CVD) are leading causes of morbidity and mortality worldwide;
therefore, seeking effective therapeutics to reduce the global burden of CVD has become …

In calcific aortic valve disease (CAVD), mechanosensitive valvular cells respond to fibrosis-
and calcification-induced tissue stiffening, further driving pathophysiology. No …

Calcific aortic valve stenosis (CAVS), the third most prevalent cardiovascular disorder is
known to impose a huge social and economic burden on patients. However, no …

Calcific aortic valve stenosis (CAVS) is the most prevalent heart valvular disease worldwide
and a slowly progressive disorder characterized by thickening of the aortic valve …

Calcific aortic valve disease (CAVD) is the most prevalent valvular heart disease in older
individuals, but there is a lack of drug treatment. The cellular biological mechanisms of …

Calcific aortic valve stenosis (CAVS) is among the most common causes of cardiovascular
mortality in an aging population worldwide. The pathomechanisms of CAVS are such a …

The most common alterations affecting mitochondria, and associated with cardiac
pathological conditions, implicate a long list of defects. They include impairments of the …

Heart valve replacement have numerous problems, such as calcification, inflammation, and
limited endothelialization. Herein, we used bio-degradable arginine-modified polylysine and …