Neuroinflammation and fibrosis in stroke: The good, the bad and the ugly
Stroke is the leading cause of death and the main cause of disability in surviving patients.
The detrimental interaction between immune cells, glial cells, and matrix components in …
The detrimental interaction between immune cells, glial cells, and matrix components in …
Investigating the Potential Mechanisms and Therapeutic Targets of Inflammatory Cytokines in Post-stroke Depression
Y Zhang, Y Yang, H Li, Q Feng, W Ge, X Xu - Molecular Neurobiology, 2024 - Springer
Post-stroke depression (PSD) affects approximately one-third of stroke survivors, severely
impacting general recovery and quality of life. Despite extensive studies, the exact …
impacting general recovery and quality of life. Despite extensive studies, the exact …
[HTML][HTML] Vagus nerve stimulation alleviated cerebral ischemia and reperfusion injury in rats by inhibiting pyroptosis via α7 nicotinic acetylcholine receptor
H Tang, J Li, Q Zhou, S Li, C Xie, L Niu, J Ma… - Cell death discovery, 2022 - nature.com
Cumulative evidence suggests that pyroptosis, a new sort of programmed cell death, is
closely related to cerebral ischemia/reperfusion (I/R) injury. Our previous studies have …
closely related to cerebral ischemia/reperfusion (I/R) injury. Our previous studies have …
Interleukin-18 from neurons and microglia mediates depressive behaviors in mice with post-stroke depression
D Wu, G Zhang, C Zhao, Y Yang, Z Miao… - Brain, behavior, and …, 2020 - Elsevier
Post-stroke depression (PSD) is a common and serious complication that is affecting one
thirds of stroke patients which leaves them with a poor quality of life, high mortality rate, high …
thirds of stroke patients which leaves them with a poor quality of life, high mortality rate, high …
[HTML][HTML] Gut microbiota composition reflects disease progression, severity and outcome, and dysfunctional immune responses in patients with hypertensive …
J Luo, Y Chen, G Tang, Z Li, X Yang, X Shang… - Frontiers in …, 2022 - frontiersin.org
Objective In this study, we aimed to explore the alterations in gut microbiota composition and
cytokine responses related to disease progression, severity, and outcomes in patients with …
cytokine responses related to disease progression, severity, and outcomes in patients with …
Interleukin‐18 mediated inflammatory brain injury after intracerebral hemorrhage in male mice
H Li, J Tian, Y Yin, S Diao, X Zhang… - Journal of …, 2022 - Wiley Online Library
Abstract Interleukin‐18 (IL‐18), a pro‐inflammatory cytokine, is thought to be associated with
inflammation in many neurological diseases such as ischemic stroke and poststroke …
inflammation in many neurological diseases such as ischemic stroke and poststroke …
[HTML][HTML] Red blood cell distribution width is associated with neuronal damage in acute ischemic stroke
RH Hong, J Zhu, ZZ Li, J Yuan, P Zhao, J Ding… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Elevated red blood cell distribution width (RDW) has been found to be associated with the
occurrence of ischemic stroke. However, there is no defined relationship between RDW and …
occurrence of ischemic stroke. However, there is no defined relationship between RDW and …
Spata2 Knockdown Exacerbates Brain Inflammation via NF-κB/P38MAPK Signaling and NLRP3 Inflammasome Activation in Cerebral Ischemia/Reperfusion Rats
Y Ren, J Jiang, W Jiang, X Zhou, W Lu, J Wang… - Neurochemical …, 2021 - Springer
Brain inflammation induced by ischemic stroke is an important cause of secondary brain
injury. The nuclear factor kappa B (NF-κB), mitogen-activated protein kinase (MAPK), and …
injury. The nuclear factor kappa B (NF-κB), mitogen-activated protein kinase (MAPK), and …
[HTML][HTML] Vinpocetine attenuates ischemic stroke through inhibiting NLRP3 inflammasome expression in mice
D Han, J Wang, L Wen, M Sun, H Liu… - Journal of …, 2021 - journals.lww.com
Ischemic stroke is the leading cause of globe death and permanent disability, but its
therapeutic strategies are limited. Over the past decades, multiprotein complexes called …
therapeutic strategies are limited. Over the past decades, multiprotein complexes called …
Exploring causal association between circulating inflammatory cytokines and functional outcomes following ischemic stroke: A bidirectional Mendelian randomization …
H Liu, Z Liu, Y Huang, Q Ding, Z Lai… - European Journal of …, 2024 - Wiley Online Library
Objectives Previous observational studies have indicated correlations between various
inflammatory cytokines and functional outcomes following ischemic stroke (IS); however, the …
inflammatory cytokines and functional outcomes following ischemic stroke (IS); however, the …