Sebaceous glands (SGs), as holocrine-secreting appendages, lubricate the skin and play a
central role in the skin barrier. Large full-thickness skin defects cause overall architecture …

Organoid generation from pluripotent stem cells is a cutting-edge technique that has created
new possibilities for modelling human organs in vitro, as well as opening avenues for …

The use of animal models for biological experiments is no longer sufficient for research
related to human life and disease. The development of organ tissues has replaced animal …

Skin plays crucial roles in the human body: besides protecting the organism from external
threats, it acts as a thermal regulator, is responsible for the sense of touch, hosts microbial …

A hallmark of plastic and reconstructive surgery is restoring form and function. Historically,
tissue procured from healthy portions of a patient's body has been used to fill defects, but …

类器官血管化是完善类器官结构, 功能及支持其体外长期存活的关键问题. 近年来,
随着类器官培养及生物工程技术的发展, 类器官血管化有了长足的进步. 本文综述了血管化类 …

Due to current technological challenges, including the complexity of precise control, low
long-term survival and success rates, difficulty in maintaining function over extended …

The understanding of complex biological systems and the development of effective precision
medicine strategies necessitate controllable and tractable experimental models. The human …

Advancements in tissue engineering enable the fabrication of complex and functional
tissues or organs. In particular, bioprinting enables controlled and accurate deposition of …

Novel drug delivery technologies and knowledge of skin anatomy have been revolutionary
in healthcare. This chapter explores the intricate structure of the skin and the use of …