Maternal microbe-specific modulation of the offspring microbiome and development during pregnancy and lactation

M Tian, Q Li, T Zheng, S Yang, F Chen, W Guan… - Gut …, 2023 - Taylor & Francis
The maternal microbiome is essential for the healthy growth and development of offspring
and has long-term effects later in life. Recent advances indicate that the maternal …

[HTML][HTML] Bovine milk microbiota: Key players, origins, and potential contributions to early-life gut development

W Guo, S Liu, MZ Khan, J Wang, T Chen… - Journal of Advanced …, 2024 - Elsevier
Background Bovine milk is a significant substitute for human breast milk and holds great
importance in infant nutrition and health. Apart from essential nutrients, bovine milk also …

Human milk oligosaccharides modify the strength of priority effects in the Bifidobacterium community assembly during infancy

MF Laursen, HM Roager - The ISME Journal, 2023 - academic.oup.com
Despite the significant role of the gut microbiota in infant health and development, little is
known about the ecological processes determining gut microbial community assembly …

Alterations of milk oligosaccharides in mothers with gestational diabetes mellitus impede colonization of beneficial bacteria and development of RORγt+ Treg cell …

X Li, X Ning, B Rui, Y Wang, Z Lei, D Yu, F Liu… - Gut …, 2023 - Taylor & Francis
Gestational diabetes mellitus (GDM) is an increasing public health concern that significantly
increases the risk of early childhood allergic diseases. Altered maternal milk glycobiome …

[HTML][HTML] Birthmode and environment-dependent microbiota transmission dynamics are complemented by breastfeeding during the first year

M Selma-Royo, L Dubois, S Manara, F Armanini… - Cell host & …, 2024 - cell.com
The composition and maturation of the early-life microbiota are modulated by a number of
perinatal factors, whose interplay in relation to microbial vertical transmission remains …

Human milk oligosaccharides, antimicrobial drugs, and the gut microbiota of term neonates: observations from the KOALA birth cohort study

DJM Barnett, MF Endika, CE Klostermann, F Gu… - Gut …, 2023 - Taylor & Francis
The infant gut microbiota affects childhood health. This pioneer microbiota may be
vulnerable to antibiotic exposures, but could be supported by prebiotic oligosaccharides …

[HTML][HTML] The Infant Gut Commensal Bacteroides dorei Presents a Generalized Transcriptional Response to Various Human Milk Oligosaccharides

S Kijner, A Cher, M Yassour - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Human milk oligosaccharides (HMOs) are a family of glycans found in breastmilk with over
200 identified structures. Despite being t​​ he third-largest solid component in breastmilk …

[HTML][HTML] CRISPR-Cas-based identification of a sialylated human milk oligosaccharides utilization cluster in the infant gut commensal Bacteroides dorei

S Kijner, D Ennis, S Shmorak, A Florentin… - Nature …, 2024 - nature.com
The infant gut microbiome is impacted by early-life feeding, as human milk oligosaccharides
(HMOs) found in breastmilk cannot be digested by infants and serve as nutrients for their gut …

[HTML][HTML] Exclusively breastfed infant microbiota develops over time and is associated with human milk oligosaccharide intakes

AS Cheema, ML Trevenen, BA Turlach… - International Journal of …, 2022 - mdpi.com
Temporal development of maternal and infant microbiomes during early life impacts short-
and long-term infant health. This study aimed to characterize bacterial dynamics within …

Analysis of microbial composition and sharing in low-biomass human milk samples: a comparison of DNA isolation and sequencing techniques

JE Spreckels, A Fernández-Pato, M Kruk… - ISME …, 2023 - academic.oup.com
Human milk microbiome studies are currently hindered by low milk bacterial/human cell
ratios and often rely on 16S rRNA gene sequencing, which limits downstream analyses …