Insights into the molecular targets and emerging pharmacotherapeutic interventions for nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease
worldwide. With no Food and Drug Administration approved drugs, current treatment options …
worldwide. With no Food and Drug Administration approved drugs, current treatment options …
Developmental origins of metabolic diseases
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …
as obese, while nearly one-third of children globally experience poor growth and …
[HTML][HTML] Human health and ocean pollution
PJ Landrigan, JJ Stegeman, LE Fleming… - Annals of global …, 2020 - ncbi.nlm.nih.gov
Background: Pollution–unwanted waste released to air, water, and land by human activity–is
the largest environmental cause of disease in the world today. It is responsible for an …
the largest environmental cause of disease in the world today. It is responsible for an …
[HTML][HTML] Overview of known plastic packaging-associated chemicals and their hazards
Global plastics production has reached 380 million metric tons in 2015, with around 40%
used for packaging. Plastic packaging is diverse and made of multiple polymers and …
used for packaging. Plastic packaging is diverse and made of multiple polymers and …
Obesity II: Establishing causal links between chemical exposures and obesity
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …
prevailing view is that obesity results from an imbalance between energy intake and …
[PDF][PDF] A quantitative proteome map of the human body
Determining protein levels in each tissue and how they compare with RNA levels is
important for understanding human biology and disease as well as regulatory processes …
important for understanding human biology and disease as well as regulatory processes …
[HTML][HTML] A review of environmental metabolism disrupting chemicals and effect biomarkers associating disease risks: Where exposomics meets metabolomics
J Sun, R Fang, H Wang, DX Xu, J Yang, X Huang… - Environment …, 2022 - Elsevier
Humans are exposed to an ever-increasing number of environmental toxicants, some of
which have gradually been elucidated to be important risk factors for metabolic diseases …
which have gradually been elucidated to be important risk factors for metabolic diseases …
[HTML][HTML] Bisphenol A and its analogues: A comprehensive review to identify and prioritize effect biomarkers for human biomonitoring
V Mustieles, SC d'Cruz, S Couderq… - Environment …, 2020 - Elsevier
Human biomonitoring (HBM) studies have demonstrated widespread and daily exposure to
bisphenol A (BPA). Moreover, BPA structural analogues (eg BPS, BPF, BPAF), used as BPA …
bisphenol A (BPA). Moreover, BPA structural analogues (eg BPS, BPF, BPAF), used as BPA …
Update on the health effects of bisphenol A: overwhelming evidence of harm
FS Vom Saal, LN Vandenberg - Endocrinology, 2021 - academic.oup.com
In 1997, the first in vivo bisphenol A (BPA) study by endocrinologists reported that feeding
BPA to pregnant mice induced adverse reproductive effects in male offspring at the low dose …
BPA to pregnant mice induced adverse reproductive effects in male offspring at the low dose …
[HTML][HTML] Non-targeted metabolomics and associations with per-and polyfluoroalkyl substances (PFAS) exposure in humans: A scoping review
Objective To summarize the application of non-targeted metabolomics in epidemiological
studies that assessed metabolite and metabolic pathway alterations associated with per-and …
studies that assessed metabolite and metabolic pathway alterations associated with per-and …