Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …

Nonhealing diabetic foot ulcers (DFUs) are a continuing clinical issue despite the improved
treatment with wound debridement, off-loading the ulcer, medication, wound dressings, and …

Oxidative damage is a critical cause of diabetic wounds. Exosomes from various stem cells
could promote wound repair. Here, we investigated the potential mechanism by which …

The transplantation of mesenchymal stem cells-derived secretome, particularly extracellular
vesicles is a promising therapy to suppress spinal cord injury-triggered neuroinflammation …

The number of patients with non-healing wounds is generally increasing globally, placing a
huge social and economic burden on every country. The complexity of the wound-healing …

Background The prevalence of diabetes among the elderly population is significant and
rising annually. One of the most severe and frequent complications of diabetes mellitus is …

Chronic wound healing has long been an unmet medical need in the field of wound repair,
with diabetes being one of the major etiologies. Diabetic chronic wounds (DCWs), especially …

As a novel cell-free strategy, mesenchymal stem cell-derived extracellular vesicles (MSC-
EVs) inherit the therapeutic potential of donor cells, and are widely used for the treatment of …

Diabetes mellitus is a type of metabolic disease characterized by hyperglycemia, primarily
caused by defects in insulin secretion, insulin action, or both. Long-term chronic …

Diabetic foot is one of the most common complications of diabetes, requiring repeated
surgical interventions and leading to amputation. In the absence of effective drugs, new …