Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms

B Brown, V Ojha, I Fricke, SA Al-Sheboul, C Imarogbe… - Vaccines, 2023 - mdpi.com
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

The rise of electroactive materials in face masks for preventing virus infections

S Zhang, N Wang, Q Zhang, R Guan, Z Qu… - … Applied Materials & …, 2023 - ACS Publications
Air-transmitted pathogens may cause severe epidemics, posing considerable threats to
public health and safety. Wearing a face mask is one of the most effective ways to prevent …

Structure of SARS-CoV-2 M protein in lipid nanodiscs

KA Dolan, M Dutta, DM Kern, A Kotecha, GA Voth… - Elife, 2022 - elifesciences.org
SARS-CoV-2 encodes four structural proteins incorporated into virions, spike (S), envelope
(E), nucleocapsid (N), and membrane (M). M plays an essential role in viral assembly by …

An ultrasensitive ELISA to assay femtomolar level SARS-CoV-2 antigen based on specific peptide and tyramine signal amplification

J Liu, S Pang, M Wang, H Yu, P Ma, T Dong… - Sensors and Actuators B …, 2023 - Elsevier
The SARS-CoV-2 spreading rapidly has aroused catastrophic public healthcare issues and
economy crisis worldwide. It plays predominant role to rapidly and accurately diagnose the …

Perturbation of the host cell Ca2+ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M

E Poggio, F Vallese, AJW Hartel, TJ Morgenstern… - Cell Death & …, 2023 - nature.com
Abstract Coronavirus disease (COVID-19) is a contagious respiratory disease caused by the
SARS-CoV-2 virus. The clinical phenotypes are variable, ranging from spontaneous …

Reconstitution of the SARS-CoV-2 ribonucleosome provides insights into genomic RNA packaging and regulation by phosphorylation

CR Carlson, AN Adly, M Bi, CJ Howard, A Frost… - Journal of Biological …, 2022 - ASBMB
The nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 is
responsible for compaction of the∼ 30-kb RNA genome in the∼ 90-nm virion. Previous …

Synthesis, insertion, and characterization of SARS-CoV-2 membrane protein within lipid bilayers

Y Zhang, S Anbir, J McTiernan, S Li, M Worcester… - Science …, 2024 - science.org
Throughout history, coronaviruses have posed challenges to both public health and the
global economy; nevertheless, methods to combat them remain rudimentary, primarily due …

Membrane remodeling and trafficking piloted by SARS-CoV-2

MC Sergio, S Ricciardi, AM Guarino, L Giaquinto… - Trends in Cell …, 2024 - cell.com
The molecular mechanisms underlying SARS-CoV-2 host cell invasion and life cycle have
been studied extensively in recent years, with a primary focus on viral entry and …

[HTML][HTML] From cell to symptoms: The role of SARS-CoV-2 cytopathic effects in the pathogenesis of COVID-19 and long COVID

P Gonzalez-Garcia, O Fiorillo Moreno… - International Journal of …, 2023 - mdpi.com
Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) infection triggers various
events from molecular to tissue level, which in turn is given by the intrinsic characteristics of …

Role of E3 ubiquitin ligases and deubiquitinating enzymes in SARS-CoV-2 infection

M Zhao, M Zhang, Z Yang, Z Zhou, J Huang… - Frontiers in Cellular …, 2023 - frontiersin.org
Ever since its emergence in 2019, COVID-19 has rapidly disseminated worldwide,
engendering a pervasive pandemic that has profoundly impacted healthcare systems and …