Engineering Saccharomyces cerevisiae for high yield production of α-amyrin via synergistic remodeling of α-amyrin synthase and expanding the storage pool

Y Yu, A Rasool, H Liu, B Lv, P Chang, H Song… - Metabolic …, 2020 - Elsevier
Abstract α-Amyrin is a plant-originated high-valued triterpene that is highly effective against
several pathological ailments. α-Amyrin production by engineered Saccharomyces …

Biocatalyst development by directed evolution

M Wang, T Si, H Zhao - Bioresource technology, 2012 - Elsevier
Biocatalysis has emerged as a great addition to traditional chemical processes for
production of bulk chemicals and pharmaceuticals. To overcome the limitations of naturally …

Phage display technology as a powerful platform for antibody drug discovery

K Nagano, Y Tsutsumi - Viruses, 2021 - mdpi.com
Antibody drugs with a high affinity and specificity are effective and safe for intractable
diseases, such as cancers and autoimmune diseases. Furthermore, they have played a …

Ribosome display: a perspective

A Plückthun - Ribosome display and related technologies: Methods …, 2012 - Springer
Ribosome display is an in vitro evolution technology for proteins. It is based on in vitro
translation, but prevents the newly synthesized protein and the mRNA encoding it from …

[图书][B] Fermentation microbiology and biotechnology

EMT El-Mansi, J Nielsen, D Mousdale, RP Carlson - 2018 - books.google.com
Fermentation Microbiology and Biotechnology, 4th Edition explores and illustrates the broad
array of metabolic pathways employed for the production of primary and secondary …

Engineered microbial host selection for value-added bioproducts from lignocellulose

RG De Paula, ACC Antoniêto, LFC Ribeiro… - Biotechnology …, 2019 - Elsevier
Lignocellulose is a rich and sustainable globally available carbon source and is considered
a prominent alternative raw material for producing biofuels and valuable chemical …

Applications of protein engineering and directed evolution in plant research

MKM Engqvist, KS Rabe - Plant physiology, 2019 - academic.oup.com
Applications of Protein Engineering and Directed Evolution in Plant Research | Plant
Physiology | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

Cellulases from thermophilic fungi: recent insights and biotechnological potential

DC Li, AC Papageorgiou - Fungi in extreme environments: ecological role …, 2019 - Springer
Thermophilic fungi have attracted considerable attention in recent years as a new source of
thermostable cellulases that could be used to improve various industrial processes, such as …

Directed evolution methods for enzyme engineering

SR Nirantar - Molecules, 2021 - mdpi.com
Enzymes underpin the processes required for most biotransformations. However, natural
enzymes are often not optimal for biotechnological uses and must be engineered for …

Novel production methods of polyhydroxyalkanoates and their innovative uses in biomedicine and industry

G Fernandez-Bunster, P Pavez - Molecules, 2022 - mdpi.com
Polyhydroxyalkanoate (PHA), a biodegradable polymer obtained from microorganisms and
plants, have been widely used in biomedical applications and devices, such as sutures …