Simvastatin attenuates aluminium chloride-induced neurobehavioral impairments through activation of TGF-β1/SMAD2 and GSK3β/β-catenin signalling pathways
MM Atef, YM Mostafa, AAM Ahmed… - Environmental Toxicology …, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease characterised by the presence of
β-amyloid plaques and acetylcholine depletion leading to neurobehavioral defects. AD was …
β-amyloid plaques and acetylcholine depletion leading to neurobehavioral defects. AD was …
SARS-CoV-2 S1 protein causes brain inflammation by reducing intracerebral acetylcholine production
N Oka, K Shimada, A Ishii, N Kobayashi, K Kondo - Iscience, 2023 - cell.com
Neurological complications that occur in SARS-CoV-2 infection, such as olfactory
dysfunction, brain inflammation, malaise, and depressive symptoms, are thought to …
dysfunction, brain inflammation, malaise, and depressive symptoms, are thought to …
A metabolomic study of the urine of rats with Alzheimer's disease and the efficacy of Ding‐Zhi‐Xiao‐Wan on the afflicted rats
Y He, Y Wang, S Liu, Z Pi, Z Liu… - Journal of separation …, 2020 - Wiley Online Library
As a well‐known traditional Chinese medicine formula, Ding‐Zhi‐Xiao‐Wan has long been
used for the routine treatment of Alzheimer's disease. However, the mechanism of Ding‐Zhi …
used for the routine treatment of Alzheimer's disease. However, the mechanism of Ding‐Zhi …
Oxyresveratrol-β-cyclodextrin mitigates streptozotocin-induced Alzheimer's model cognitive impairment, histone deacetylase activity in rats: in silico & in vivo studies
T Agarwal, S Manandhar, AC Famurewa, PC Gurram… - Scientific Reports, 2024 - nature.com
Alzheimer's disease (AD) is associated with cognitive deficits and epigenetic deacetylation
that can be modulated by natural products. The role of natural oxyresveratrol-β-cyclodextrin …
that can be modulated by natural products. The role of natural oxyresveratrol-β-cyclodextrin …
Impact of Donepezil on Brain Glucose Metabolism Assessed Using [18F]2-Fluoro-2-deoxy-D-Glucose Positron Emission Tomography Imaging in a Mouse Model of …
G Hugon, S Goutal, M Sarazin, M Bottlaender… - Frontiers in …, 2022 - frontiersin.org
Translational methods are needed to monitor the impact of the Alzheimer's disease (AD) and
therapies on brain function in animal models and patients. The formation of amyloid plaques …
therapies on brain function in animal models and patients. The formation of amyloid plaques …
[HTML][HTML] Quercetin ameliorates cognitive deficit, expression of amyloid precursor gene, and pro-inflammatory cytokines in an experimental models of Alzheimer's …
E Safarzadeh, S Ataei, M Akbari, R Abolhasani… - Experimental …, 2024 - Elsevier
Chronic stress (CS) is critically involved in the Alzheimer's disease (AD) pathogenesis
resulting in cognitive disturbance. Also, amyloid precursor protein (APP) related gens, pro …
resulting in cognitive disturbance. Also, amyloid precursor protein (APP) related gens, pro …
Anti-inflammatory, anticholinesterase, antioxidant, and memory enhancement potential of Phyllanthus amarus in potassium-dichromate induced neurotoxicity of male …
KA Iteire, TJ Gbayisomore, OM Olatuyi - Journal of Chemical …, 2023 - Elsevier
This study investigated the protective effect of aqueous Phyllanthus amarus leaf extract
(APALE) in Potassium dichromate (PDc)-induced neurotoxicity. Seventy young adult male …
(APALE) in Potassium dichromate (PDc)-induced neurotoxicity. Seventy young adult male …
The Effect of Donepezil Hydrochloride in the Twitcher Mouse Model of Krabbe Disease
P Papakyriakopoulou, G Valsami, KK Dev - Molecular Neurobiology, 2024 - Springer
Krabbe disease (KD) is a rare demyelinating disorder characterized by demyelination
caused by mutations in the GALC gene, resulting in toxic accumulation of psychosine …
caused by mutations in the GALC gene, resulting in toxic accumulation of psychosine …
The additive memory and healthspan enhancement effects by the combined treatment of mature silkworm powders and Korean angelica extracts
P Nguyen, KY Kim, AY Kim, SK Kang… - Journal of …, 2021 - Elsevier
Abstracts Ethnopharmacological relevance Silkworm (Bombyx mori) and Korean angelica
(KoAg; Angelica gigas Nakai) have been widely used as traditional oriental medicines in …
(KoAg; Angelica gigas Nakai) have been widely used as traditional oriental medicines in …
Novel naringin tablet formulations of agro-resides based nano/micro crystalline cellulose with neuroprotective and Alzheimer ameliorative potentials
WA Helmy, TIM Ragab, BM Salama, M Basha… - International Journal of …, 2023 - Elsevier
This study aimed to prepare micro/nanocrystalline cellulose-loaded naringin (NAR) tablets
and evaluate their neuro-protective/therapeutic potentials in Alzheimer's disease (AD) …
and evaluate their neuro-protective/therapeutic potentials in Alzheimer's disease (AD) …