Damage to myelin is a key feature of multiple sclerosis (MS) pathology. Magnetic resonance
imaging (MRI) has revolutionized our ability to detect and monitor MS pathology in vivo …

Deep medullary veins drain into subependymal veins with four convergence zones and
show parallel distribution patterns adjacent to the body or inferior horn and a radial pattern …

Clinicians involved with different aspects of the care of persons with multiple sclerosis (MS)
and scientists with expertise on clinical and imaging techniques convened in Dallas, TX …

Background: Advanced magnetic resonance imaging (MRI) methods can provide more
specific information about various microstructural tissue changes in multiple sclerosis (MS) …

Background: Reduced myelin water fraction (MWF, a marker for myelin), increased
geometric mean T2 (ieGMT2, reflecting intra/extracellular water properties), and increased …

Recent findings showing that epidermal growth factor (EGF) is significantly decreased in the
cerebrospinal fluid (CSF) and spinal cord (SC) of living or deceased multiple sclerosis (MS) …

There are reports that astrocyte perivascular endfeet are damaged in some cases of multiple
sclerosis (MS). This study was designed to determine the origin and outcome of astrocyte …

MRI enables detailed in vivo depiction of multiple sclerosis (MS) pathology. Localized areas
of MS damage, commonly referred to as lesions, or plaques, have been a focus of clinical …

The pathogenesis of multiple sclerosis (MS) remains enigmatic and controversial. Myelin
sheaths in the central nervous system (CNS) insulate axons and allow saltatory nerve …

ABSTRACT BACKGROUND AND PURPOSE Multiple sclerosis (MS) diffusely abnormal
white matter (DAWM) is a mildly hyperintense magnetic resonance imaging abnormality …