Increased interest in the aging and Alzheimer's disease (AD)-related impairments in
autophagy in the brain raise important questions about regulation and treatment. Since …

Since prehistory, human species have depended on plants for both food and medicine.
Even in countries with ready access to modern medicines, alternative treatments are still …

There are currently no drugs known to rescue the function of Kv1. 1 voltage-gated potassium
channels carrying loss-of-function sequence variants underlying the inherited movement …

Acid-sensing ion channels (ASICs) are proton-gated ion channels that contribute to pain
perception and neurotransmission. Being involved in sensing inflammation and ischemia …

Stomatal movement is indispensable for plant growth and survival in response to
environmental stimuli. Cytosolic Ca2+ elevation plays a crucial role in ABA‐induced …

The evergreen plant rosemary (Salvia rosmarinus) has been employed medicinally for
centuries as a memory aid, analgesic, spasmolytic, vasorelaxant and antihypertensive, with …

Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality,
imposing an increasing global health burden. Cardiac ion channels (voltage-gated Na V, Ca …

Tree and shrub barks have been used as folk medicine by numerous cultures across the
globe for millennia, for a variety of indications, including as vasorelaxants and …

Abstract The phytochemical, polyphenolic compound,(-)-epigallocatechin-3-gallate (EGCG),
is the main catechin found in green tea. Although a modulatory effect of EGCG on voltage …

Green tea intake has been demonstrated to protect against arterial embolism and
thrombosis in previous observational studies. However, whether there is a causative …