Diagnostic biomarkers in ovarian cancer: advances beyond CA125 and HE4

A Ghose, L McCann, S Makker… - … in medical oncology, 2024 - journals.sagepub.com
Ovarian cancer (OC) is the most lethal gynaecologic malignancy, attributed to its insidious
growth, non-specific symptoms and late presentation. Unfortunately, current screening …

Niraparib and advanced ovarian cancer: A beacon in the non-BRCA mutated setting

MFP Maiorano, BA Maiorano, A Biancofiore, G Cormio… - Pharmaceuticals, 2023 - mdpi.com
Ovarian cancer (OC) is the eighth most common cancer among the female population and
the most lethal of all the female reproductive system malignancies. Poly (ADP-ribose) …

Metronomic chemotherapy in ovarian cancer

V Garg, L Kumar - Cancer Letters, 2023 - Elsevier
Translational research and the development of targeted therapies have transformed the
therapeutic landscape in epithelial ovarian cancer over the last decade. However, recurrent …

The efficacy and toxicity of mirvetuximab soravtansine, a novel antibody-drug conjugate, in the treatment of advanced or recurrent ovarian cancer: a meta-analysis

K Xu, T Wang, S Pan, J He - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction This meta-analysis aims to systematically analyze the efficacy and toxicity of
mirvetuximab soravtansine (MIRV) as second-line and above treatment for advanced or …

Revisiting the advances and challenges in the clinical applications of extracellular vesicles in cancer

G He, J Liu, Y Yu, S Wei, X Peng, L Yang, H Li - Cancer Letters, 2024 - Elsevier
Extracellular vesicles (EVs) have been the subject of an exponentially growing number of
studies covering their biogenesis mechanisms, isolation and analysis techniques …

The Putative Effects of Neoadjuvant Chemotherapy on the Immune System of Advanced Epithelial Ovarian Carcinoma

Y Li, X Gan, F Li, L Hu - Immunological investigations, 2024 - Taylor & Francis
The epithelial ovarian carcinoma (EOC) is one of leading causes of cancer-related mortality
in females. For some patients, complete resection cannot be achieved, thus neoadjuvant …

[HTML][HTML] The power and the promise of synthetic lethality for clinical application in cancer treatment

QW Liu, ZW Yang, QH Tang, WE Wang, DS Chu… - Biomedicine & …, 2024 - Elsevier
Synthetic lethality is a phenomenon wherein the simultaneous deficiency of two or more
genes results in cell death, while the deficiency of any individual gene does not lead to cell …

Deguelin Restores Paclitaxel Sensitivity in Paclitaxel-Resistant Ovarian Cancer Cells via Inhibition of the EGFR Signaling Pathway

S Bae, S Bae, HS Kim, YJ Lim, G Kim… - Cancer Management …, 2024 - Taylor & Francis
Background Ovarian cancer is one of women's malignancies with the highest mortality
among gynecological cancers. Paclitaxel is used in first-line ovarian cancer chemotherapy …

Evaluating the efficacy and safety of trebananib in treating ovarian cancer and non-ovarian cancer patients: a meta-analysis and systematic review

J Zhang, J Su, Y Zhou, J Lu - Expert Review of Anticancer Therapy, 2024 - Taylor & Francis
Objectives Due to its anti-angiogenic properties, trebananib is frequently employed in the
treatment of cancer patients, particularly those with ovarian cancer. We conducted a meta …

[HTML][HTML] 12-O-deacetyl-phomoxanthone A inhibits ovarian tumor growth and metastasis by downregulating PDK4

C Yang, S Xing, X Wei, J Lu, G Zhao, X Ma… - Biomedicine & …, 2024 - Elsevier
Aims The xanthone dimer 12-O-deacetyl-phomoxanthone A (12-ODPXA) was extracted from
the secondary metabolites of the endophytic fungus Diaporthe goulteri. The 12-ODPXA …