Extracellular vesicles (EVs) have been the subject of an exponentially growing number of
studies covering their biogenesis mechanisms, isolation and analysis techniques …

The epithelial ovarian carcinoma (EOC) is one of leading causes of cancer-related mortality
in females. For some patients, complete resection cannot be achieved, thus neoadjuvant …

Translational research and the development of targeted therapies have transformed the
therapeutic landscape in epithelial ovarian cancer over the last decade. However, recurrent …

Synthetic lethality is a phenomenon wherein the simultaneous deficiency of two or more
genes results in cell death, while the deficiency of any individual gene does not lead to cell …

Background Ovarian cancer is one of women's malignancies with the highest mortality
among gynecological cancers. Paclitaxel is used in first-line ovarian cancer chemotherapy …

Ovarian cancer (OC) is the most lethal gynaecologic malignancy, attributed to its insidious
growth, non-specific symptoms and late presentation. Unfortunately, current screening …

Aims The xanthone dimer 12-O-deacetyl-phomoxanthone A (12-ODPXA) was extracted from
the secondary metabolites of the endophytic fungus Diaporthe goulteri. The 12-ODPXA …

Background Ovarian clear cell carcinoma (OCCC) is a rare pathological histotype in ovarian
cancer, while the survival rate of advanced OCCC (Stage III-IV) is substantially lower than …

Ovarian cancer (OC) is the eighth most common cancer among the female population and
the most lethal of all the female reproductive system malignancies. Poly (ADP-ribose) …

Ovarian cancer is the leading cause of gynecologic cancer death. Among the most
innovative anti-cancer approaches, the genetic concept of synthetic lethality is that mutations …