Apoptotic mechanisms of quercetin in liver cancer: recent trends and advancements

G Sethi, P Rath, A Chauhan, A Ranjan, R Choudhary… - Pharmaceutics, 2023 - mdpi.com
Due to rising incidence rates of liver cancer and worries about the toxicity of current
chemotherapeutic medicines, the hunt for further alternative methods to treat this malignancy …

Advanced phytochemical-based nanocarrier systems for the treatment of breast cancer

VP Chavda, LV Nalla, P Balar, R Bezbaruah… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is a concern for the healthcare system. Even with the
advancement of science and technology, the current system for therapeutics and diagnostics …

Relationship between antioxidant and anticancer activity of trihydroxyflavones

I Grigalius, V Petrikaite - Molecules, 2017 - mdpi.com
Plant polyphenols have been highlighted not only as chemopreventive, but also as potential
anticancer substances. Flavones are a subclass of natural flavonoids reported to have an …

Role of curcumin in regulating p53 in breast cancer: An overview of the mechanism of action

WH Talib, SA Al-Hadid, MBW Ali… - … Cancer: Targets and …, 2018 - Taylor & Francis
p53 is a tumor suppressor gene involved in various cellular mechanisms including DNA
repair, apoptosis, and cell cycle arrest. More than 50% of human cancers have a mutated …

Ginseng on cancer: potential role in modulating inflammation-mediated angiogenesis

D Dai, CF Zhang, S Williams, CS Yuan… - The American journal of …, 2017 - World Scientific
Angiogenesis is a regulated process integral to many physiological and pathological
situations, including carcinogenesis and tumor growth. The majority of the angiogenic …

Polyphenol-rich extract induces apoptosis with immunogenic markers in melanoma cells through the ER stress-associated kinase PERK

K Prieto, Y Cao, E Mohamed, J Trillo-Tinoco… - Cell death …, 2019 - nature.com
Polyphenols elicit antitumor activities, in part, through the induction of anti-or pro-oxidant
effects in cancer cells which promote priming of protective anti-tumor immunity. We recently …

Curcumin reduces colorectal cancer cell proliferation and migration and slows in vivo growth of liver metastases in rats

B Herrero de la Parte, M Rodeño-Casado… - Biomedicines, 2021 - mdpi.com
Background: New therapeutic approaches are an essential need for patients suffering from
colorectal cancer liver metastases. Curcumin, a well-known plant-derived polyphenol, has …

Synthesis, Characterization, and Antimicrobial and Antiproliferative Effects of CuO-TiO2-Chitosan-Escin Nanocomposites on Human Leukemic MOLT4 Cells

AY Elderdery, AH Alhamidi, AME Elkhalifa… - Nanomaterials, 2022 - mdpi.com
Nanocomposites comprised of CuO-TiO2-chitosan-escin, which has adjustable
physicochemical properties, provide a solution for therapeutic selectivity in cancer treatment …

Pancreatic cancer therapy review: from classic therapeutic agents to modern nanotechnologies

A Rebelo, J Molpeceres, P Rijo… - Current drug …, 2017 - ingentaconnect.com
Pancreatic cancer remains one of the most lethal cancers worldwide, with an extremely poor
prognosis. This cancer is considered the 5th leading cause of cancer related death. The …

Involvement of phytochemical-encapsulated nanoparticles' interaction with cellular signalling in the amelioration of benign and malignant brain tumours

S Mehan, N Arora, S Bhalla, A Khan, MU Rehman… - Molecules, 2022 - mdpi.com
Brain tumours have unresolved challenges that include delay prognosis and lower patient
survival rate. The increased understanding of the molecular pathways underlying cancer …