[HTML][HTML] Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy

G Oberdörster, A Maynard, K Donaldson… - Particle and fibre …, 2005 - Springer
The rapid proliferation of many different engineered nanomaterials (defined as materials
designed and produced to have structural features with at least one dimension of 100 …

Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles

P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

[HTML][HTML] Quercetin prevents LPS-induced oxidative stress and inflammation by modulating NOX2/ROS/NF-kB in lung epithelial cells

OJ Sul, SW Ra - Molecules, 2021 - mdpi.com
Oxidative stress caused by the production of reactive oxygen species (ROS) plays a major
role in inflammatory processes. We hypothesized that modulation of ROS via quercetin may …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis

B Fubini, A Hubbard - Free radical Biology and medicine, 2003 - Elsevier
Exposure to particulate silica (most crystalline polymorphs) causes a persistent inflammation
sustained by the release of oxidants in the alveolar space. Reactive oxygen species (ROS) …

Oxidative stress and regulation of glutathione in lung inflammation

I Rahman, W MacNee - European Respiratory Journal, 2000 - Eur Respiratory Soc
Inflammatory lung diseases are characterized by chronic inflammation and
oxidant/antioxidant imbalance, a major cause of cell damage. The development of an …

Ambient particle inhalation and the cardiovascular system: potential mechanisms.

K Donaldson, V Stone, A Seaton… - Environmental health …, 2001 - ehp.niehs.nih.gov
Well-documented air pollution episodes throughout recent history have led to deaths among
individuals with cardiovascular and respiratory disease. Although the components of air …

Rapid increases in the steady-state concentration of reactive oxygen species in the lungs and heart after particulate air pollution inhalation.

SA Gurgueira, J Lawrence, B Coull… - Environmental …, 2002 - ehp.niehs.nih.gov
In vitro studies suggest that reactive oxygen species contribute to the cardiopulmonary
toxicity of particulate air pollution. To evaluate the ability of particulate air pollution to …

Silica binding and toxicity in alveolar macrophages

RF Hamilton Jr, SA Thakur, A Holian - Free Radical Biology and Medicine, 2008 - Elsevier
Inhalation of the crystalline form of silica is associated with a variety of pathologies, from
acute lung inflammation to silicosis, in addition to autoimmune disorders and cancer. Basic …

Short-term exposure to air pollution and lung function in the Framingham Heart Study

MB Rice, PL Ljungman, EH Wilker, DR Gold… - American journal of …, 2013 - atsjournals.org
Rationale: Short-term exposure to ambient air pollution has been associated with lower lung
function. Few studies have examined whether these associations are detectable at relatively …

Cytotoxicity, DNA damage, and apoptosis induced by titanium dioxide nanoparticles in human non-small cell lung cancer A549 cells

Y Wang, H Cui, J Zhou, F Li, J Wang, M Chen… - … Science and Pollution …, 2015 - Springer
Concerns about the risk of titanium dioxide nanoparticles (TiO 2 NPs) to human health and
environment are gradually increasing due to their wide range of applications. In this study …