Silk fibroin/hydroxyapatite composites for bone tissue engineering

M Farokhi, F Mottaghitalab, S Samani… - Biotechnology …, 2018 - Elsevier
Silk fibroin (SF) is a natural fibrous polymer with strong potential for many biomedical
applications. SF has attracted interest in the field of bone tissue engineering due to its …

Bone-targeted nanoparticle drug delivery system: an emerging strategy for bone-related disease

Y Chen, X Wu, J Li, Y Jiang, K Xu, J Su - Frontiers in Pharmacology, 2022 - frontiersin.org
Targeted delivery by either systemic or local targeting of therapeutics to the bone is an
attractive treatment for various bone metabolism diseases such as osteoporosis …

[图书][B] Bone mechanics handbook

SC Cowin - 2001 - taylorfrancis.com
This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …

Targeted delivery to bone and mineral deposits using bisphosphonate ligands

LE Cole, T Vargo-Gogola, RK Roeder - Advanced drug delivery reviews, 2016 - Elsevier
The high concentration of mineral present in bone and pathological calcifications is unique
compared with all other tissues and thus provides opportunity for targeted delivery of …

Bone tissue engineering with premineralized silk scaffolds

HJ Kim, UJ Kim, HS Kim, C Li, M Wada, GG Leisk… - Bone, 2008 - Elsevier
Silk fibroin biomaterials are being explored as novel protein-based systems for cell and
tissue culture. In the present study, biomimetic growth of calcium phosphate on porous silk …

Biomimetic mineralization of collagen by combined fibril assembly and calcium phosphate formation

JH Bradt, M Mertig, A Teresiak, W Pompe - Chemistry of Materials, 1999 - ACS Publications
To find new ways for the synthesis of improved bone implant materials, we studied the
mineralization of collagen in vitro. Collagen was mineralized by combining the collagen fibril …

Biomineralization: conflicts, challenges, and opportunities

AL Boskey - Journal of cellular biochemistry, 1998 - Wiley Online Library
Biomineralization is the process by which mineral crystals are deposited in an organized
fashion in the matrix (either cellular or extracellular) of living organisms. Over the past 25 …

'Magic bullets' for bone diseases: progress in rational design of bone-seeking medicinal agents

S Zhang, G Gangal, H Uludağ - Chemical Society Reviews, 2007 - pubs.rsc.org
An ideal therapeutic agent for bone diseases should act solely on bone tissue with no
pharmacological activity at other anatomical sites. Current therapeutic agents, however, do …

New developments in polymer-controlled, bioinspired calcium phosphate mineralization from aqueous solution

K Bleek, A Taubert - Acta biomaterialia, 2013 - Elsevier
The polymer-controlled and bioinspired precipitation of inorganic minerals from aqueous
solution at near-ambient or physiological conditions avoiding high temperatures or organic …

Tissue engineering: state of the art in oral rehabilitation

EL Scheller, PH Krebsbach… - Journal of oral …, 2009 - Wiley Online Library
More than 85% of the global population requires repair or replacement of a craniofacial
structure. These defects range from simple tooth decay to radical oncologic craniofacial …