Rates of obesity and diabetes have increased significantly over the past decades and the
prevalence is expected to continue to rise further in the coming years. Many observations …

This Review focuses on the mechanistic evidence for a link between obesity, dysregulated
cellular metabolism and breast cancer. Strong evidence now links obesity with the …

Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Adiponectin is one of the most important adipocytokines secreted by adipocytes and is
called a “guardian angel adipocytokine” owing to its unique biological functions. Adiponectin …

The number of cancer cases caused by being obese is estimated to be 20% with the
increased risk of malignancies being influenced by diet, weight change, and body fat …

Breast cancer accounts for 25% of all types of cancer in women, and triple negative breast
cancer (TNBC) comprises around 15~ 20% of breast cancers. Conventional chemotherapy …

Cytokines are highly inducible, secretory proteins that mediate intercellular communication
in the immune system. They are grouped into several protein families that are referred to as …

Existing explanations of obesity-associated cancer emphasise direct mutagenic effects of
dietary components or hormonal imbalance. Some of these hypotheses are reviewed briefly …

Cross-talk between adipose tissue and central nervous system (CNS) underlies the
increased risk of obese people to develop brain diseases such as cognitive and mood …

The prevalence and severity of obesity have increased in recent years, likely the result of
complex interactions between genes, dietary intake, physical activity, and the environment …