Osteosarcopenia (OS) is defined by the concurrent presence of osteopenia/osteoporosis
and sarcopenia. The pathogenesis and etiology of OS involve genetic, biochemical …

Estrogens (estradiol, estriol, and estrone) are important hormones that directly and indirectly
regulate the metabolism and function of bone and skeletal muscle via estrogen receptors …

The skeletal system contains a series of sophisticated cellular lineages arising from the
mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs) that determine the …

Identification of cues originating from skeletal muscle that govern bone formation is essential
for understanding the crosstalk between muscle and bone and for developing therapies for …

Vitamin D deficiency frequently occurs in older people, especially in individuals with
comorbidity and polypharmacotherapy. In this group, low vitamin D plasma concentration is …

Abstract The South Asian population is rapidly ageing and sarcopenia is likely to become a
huge burden in this region if proper action is not taken in time. Several sarcopenia …

Animal models are fundamental to advance our knowledge of the underlying
pathophysiology of bone loss and to study pharmaceutical countermeasures against it. The …

The human microbiota functions at the interface between diet, medication-use, lifestyle, host
immune development and health. It is therefore closely aligned with many of the recognised …

Sarcopenia and osteoporosis are common musculoskeletal comorbidities of chronic
obstructive pulmonary disease (COPD) that seriously affect the quality of life and prognosis …

Osteosarcopenia is defined as the concurrent occurrence of osteopenia/osteoporosis and
sarcopenia. The aim of the current study was to perform a systematic review with meta …