CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts

J Guo, YJ Zhou, ML Hillwig, Y Shen… - Proceedings of the …, 2013 - National Acad Sciences
Cytochrome P450 enzymes (CYPs) play major roles in generating highly functionalized
terpenoids, but identifying the exact biotransformation step (s) catalyzed by plant CYP in …

Facile room-temperature synthesis of a spherical mesoporous covalent organic framework for ultrasensitive solid-phase microextraction of phenols prior to gas …

L Liu, WK Meng, L Li, GJ Xu, X Wang, LZ Chen… - Chemical Engineering …, 2019 - Elsevier
High-performance extraction of polar phenols from aqueous samples is challenging
because of their hydrophilicity, extremely low concentration, and complicated matrices …

Danshen: a phytochemical and pharmacological overview

XD MEIm, C Yan-Feng, C Yan-Yun, LI Jing… - Chinese journal of …, 2019 - Elsevier
Danshen, the dried root or rhizome of Salvia miltiorrhiza Bge., is a traditional and folk
medicine in Asian countries, especially in China and Japan. In this review, we summarized …

Salvia miltiorrhiza: a potential red light to the development of cardiovascular diseases

L Wang, R Ma, C Liu, H Liu, R Zhu… - Current …, 2017 - ingentaconnect.com
Salvia miltiorrhiza Bunge, also known as Danshen in Chinese, has been widely used to treat
cardiovascular diseases (CVD) in China and other Asia countries. Here, we summarize …

Cardiovascular actions and therapeutic potential of tanshinone IIA

S Gao, Z Liu, H Li, PJ Little, P Liu, S Xu - Atherosclerosis, 2012 - Elsevier
Tanshinone IIA (TS), a pharmacologically active component isolated from the rhizome of the
Chinese herb Salvia miltiorrhiza Bunge (Danshen), has been clinically used in Asian …

Cardiovascular effects of Danshen

TO Cheng - International journal of cardiology, 2007 - Elsevier
Danshen is one of the most versatile Chinese herbal drugs that have been used for hundred
of years in the treatment of numerous ailments. Because of its properties of improving …

Ferroptosis in lung cancer: a novel pathway regulating cell death and a promising target for drug therapy

N Xing, Q Du, S Guo, G Xiang, Y Zhang, X Meng… - Cell Death …, 2023 - nature.com
Lung cancer is a common malignant tumor that occurs in the human body and poses a
serious threat to human health and quality of life. The existing treatment methods mainly …

Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection

JHC Ho, CY Hong - Journal of biomedical science, 2011 - Springer
Salvianolic acids are the most abundant water-soluble compounds extracted from Radix
Salvia miltiorrhiza (Danshen). In China, Danshen has been wildly used to treat …

[HTML][HTML] Effects of biotic and abiotic elicitors on cell growth and tanshinone accumulation in Salvia miltiorrhiza cell cultures

JL Zhao, LG Zhou, JY Wu - Applied Microbiology and Biotechnology, 2010 - Springer
This study examined the effects of biotic and abiotic elicitors on the production of diterpenoid
tanshinones in Salvia miltiorrhiza cell culture. Four classes of elicitors were tested, heavy …

Salvia miltiorrhiza in diabetes: A review of its pharmacology, phytochemistry, and safety

Q Jia, R Zhu, Y Tian, B Chen, R Li, L Li, L Wang, Y Che… - Phytomedicine, 2019 - Elsevier
Background Salvia miltiorrhiza (SM), one of the frequently used herbs in traditional Chinese
medicine (TCM), has now attracted rising interests for a possible alternative in the …