Ionic liquid surfactant‐mediated ultrasonic‐assisted extraction coupled to HPLC: Application to analysis of tanshinones in Salvia miltiorrhiza bunge

K Wu, Q Zhang, Q Liu, F Tang… - Journal of Separation …, 2009 - Wiley Online Library
Ionic liquid surfactants are a class of ionic liquids (ILs), which can form micelles in the
aqueous solution. In this paper, we demonstrate a novel extracting system based on the use …

[HTML][HTML] R2R3-MYB Transcription Factor SmMYB52 Positively Regulates Biosynthesis of Salvianolic Acid B and Inhibits Root Growth in Salvia miltiorrhiza

R Yang, S Wang, H Zou, L Li, Y Li, D Wang… - International Journal of …, 2021 - mdpi.com
The dried root of Salvia miltiorrhiza is a renowned traditional Chinese medicine that was
used for over 1000 years in China. Salvianolic acid B (SalB) is the main natural bioactive …

Salvianolic acid B inhibits growth of head and neck squamous cell carcinoma in vitro and in vivovia cyclooxygenase‐2 and apoptotic pathways

Y Hao, T Xie, A Korotcov, Y Zhou… - … Journal of Cancer, 2009 - Wiley Online Library
Abstract Overexpression of cyclooxygenase‐2 (COX‐2) in oral mucosa has been associated
with increased risk of head and neck squamous cell carcinoma (HNSCC). Celecoxib is a …

Tanshinone II A enhances pyroptosis and represses cell proliferation of HeLa cells by regulating miR-145/GSDMD signaling pathway

W Tong, J Guo, C Yang - Bioscience reports, 2020 - portlandpress.com
Cervical cancer is the fourth most common cancer in women globally. Lack of effective
pharmacotherapies for cervical cancer mainly attributed to an elusive understanding of the …

Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells

D Xu, TH Lin, S Li, J Da, XQ Wen, J Ding, C Chang… - Cancer Letters, 2012 - Elsevier
Androgen receptor (AR) is the major therapeutic target for the treatment of prostate cancer
(PCa). Anti-androgens to reduce or prevent androgens binding to AR are widely used to …

[HTML][HTML] Anti-cancer effect of danshen and dihydroisotanshinone I on prostate cancer: targeting the crosstalk between macrophages and cancer cells via inhibition of …

CY Wu, YH Yang, YY Lin, FC Kuan, YS Lin, WY Lin… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Abstract Danshen (Salvia miltiorrhiza Bunge) is widely used in traditional Chinese medicine.
In our study, the in vivo protective effect of danshen in prostate cancer patients was validated …

Antiproliferative activity of abietane diterpenoids against human tumor cells

O Burmistrova, MF Simões, P Rijo… - Journal of natural …, 2013 - ACS Publications
In the present study, the cytotoxicity of 30 diterpenoids with an abietane or a halimane
skeleton was determined against five human tumor cell lines (HL-60, U937, Molt-3, SK-MEL …

[HTML][HTML] Drug Repurposing to Circumvent Immune Checkpoint Inhibitor Resistance in Cancer Immunotherapy

KKW To, WC Cho - Pharmaceutics, 2023 - mdpi.com
Immune checkpoint inhibitors (ICI) have achieved unprecedented clinical success in cancer
treatment. However, drug resistance to ICI therapy is a major hurdle that prevents cancer …

TanshinoneáIIA induces growth inhibition and apoptosis in gastric cancer in vitro and in vivo

J Chen, DY Shi, SL Liu, L Zhong - Oncology reports, 2012 - spandidos-publications.com
As a phytochemical derived from the roots of Salvia miltiorrhiza Bunge, TanshinoneáIIA has
been reported to possess anti-inflammatory and antioxidant activity. Studies in breast, colon …

Ursolic acid from the Chinese herb danshen (Salvia miltiorrhiza L.) upregulates eNOS and downregulates Nox4 expression in human endothelial cells

K Steinkamp-Fenske, L Bollinger, N Völler, H Xu, Y Yao… - Atherosclerosis, 2007 - Elsevier
Danshen, the dried root of Salvia miltiorrhiza Bunge (Lamiaceae), is one of the most
commonly used traditional Chinese medicines for cardiovascular indications. In EA. hy 926 …