Chemical derivatization of natural products: Semisynthesis and pharmacological aspects-A decade update

S Majhi, D Das - Tetrahedron, 2021 - Elsevier
Natural products and their semisynthetic derivatives continue to be an important source of
potential drug leads. Natural products and their analogues structures possess the …

Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion

JY Han, JY Fan, Y Horie, S Miura, DH Cui… - Pharmacology & …, 2008 - Elsevier
Ischemia and reperfusion (I/R) exerts multiple insults in microcirculation, frequently
accompanied by endothelial cell injury, enhanced adhesion of leukocytes, macromolecular …

Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach

KH Lee - Journal of natural products, 2010 - ACS Publications
Medicinal plants have long been an excellent source of pharmaceutical agents. Accordingly,
the long-term objectives of the author's research program are to discover and design new …

Salvia miltiorrhiza: an ancient Chinese herbal medicine as a source for anti-osteoporotic drugs

Y Guo, Y Li, L Xue, RP Severino, S Gao, J Niu… - Journal of …, 2014 - Elsevier
Abstract Ethnopharmacological relevance Red sage (Salvia miltiorrhiza Bunge), also known
as Danshen in Chinese, has been used historically and is currently exploited in combination …

Tanshinones: sources, pharmacokinetics and anti-cancer activities

Y Zhang, P Jiang, M Ye, SH Kim, C Jiang… - International journal of …, 2012 - mdpi.com
Tanshinones are a class of abietane diterpene compound isolated from Salvia miltiorrhiza
(Danshen or Tanshen in Chinese), a well-known herb in Traditional Chinese Medicine …

Total synthesis of natural products containing benzofuran rings

MM Heravi, V Zadsirjan, H Hamidi, PHT Amiri - RSC advances, 2017 - pubs.rsc.org
Research on natural products containing benzofuran has remarkably increased during the
past few decades. Newly isolated natural products with complex structures are being …

A functional genomics approach to tanshinone biosynthesis provides stereochemical insights

W Gao, ML Hillwig, L Huang, G Cui, X Wang… - Organic …, 2009 - ACS Publications
Tanshinones are abietane-type norditerpenoid quinone natural products that are the
bioactive components of the Chinese medicinal herb Salvia miltiorrhiza Bunge. The initial …

[HTML][HTML] Recent progress of research on herbal products used in traditional Chinese medicine: the herbs belonging to the divine Husbandman's herbal foundation …

KH Lee, S Morris-Natschke, K Qian, Y Dong… - Journal of Traditional …, 2012 - Elsevier
This article will review selected herbal products from Chinese Materia Medica that are used
in Traditional Chinese Medicine. The herbs come from the upper, middle, and lower class …

The effect of salvianolic acid on vascular protection and possible mechanisms

Y Wu, S Xu, XY Tian - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
Salvia miltiorrhiza (Danshen), as an important traditional Chinese medicinal plant, has been
used in China for the treatment of cardiovascular diseases for hundreds of years. Salvianolic …

Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza

W Gao, HX Sun, H Xiao, G Cui, ML Hillwig, A Jackson… - BMC genomics, 2014 - Springer
Background Plant natural products have been co-opted for millennia by humans for various
uses such as flavor, fragrances, and medicines. These compounds often are only produced …