[HTML][HTML] Molecular cloning and expression analysis of WRKY transcription factor genes in Salvia miltiorrhiza

C Li, D Li, F Shao, S Lu - BMC genomics, 2015 - Springer
Background WRKY proteins comprise a large family of transcription factors and play
important regulatory roles in plant development and defense response. The WRKY gene …

Tanshinone IIA exhibits anticonvulsant activity in zebrafish and mouse seizure models

OE Buenafe, A Orellana-Paucar, J Maes… - ACS chemical …, 2013 - ACS Publications
Danshen or Chinese red sage (Salvia miltiorrhiza, Bunge) is used by traditional Chinese
medicine (TCM) practitioners to treat neurological, cardiovascular, and cerebrovascular …

Metabolites profile of Xian-Ling-Gu-Bao capsule, a traditional Chinese medicine prescription, in rats by ultra performance liquid chromatography coupled with …

J Geng, Y Dai, Z Yao, Z Qin, X Wang, L Qin… - Journal of Pharmaceutical …, 2014 - Elsevier
Abstract Xian-Ling-Gu-Bao capsule (XLGB), a well-known traditional Chinese medicine
prescription (TCMP), is widely used for the treatment of osteoporosis. However, due to lack …

Cytotoxic Effects of Tanshinones from Salvia miltiorrhiza on Doxorubicin-Resistant Human Liver Cancer Cells

WYW Lee, CCM Cheung, KWK Liu… - Journal of natural …, 2010 - ACS Publications
P-Glycoprotein (Pgp) overexpression and alterations in p53 oncogene expression are
known to affect chemotherapeutic efficacy in the treatment of human hepatocellular …

Tanshinone I Activates the Nrf2-Dependent Antioxidant Response and Protects Against As(III)-Induced Lung Inflammation In Vitro and In Vivo

S Tao, Y Zheng, A Lau, MC Jaramillo… - Antioxidants & redox …, 2013 - liebertpub.com
Abstract Aims: The NF-E2 p45-related factor 2 (Nrf2) signaling pathway regulates the
cellular antioxidant response and activation of Nrf2 has recently been shown to limit tissue …

Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway

YT Ye, W Zhong, P Sun, D Wang, C Wang… - Journal of …, 2017 - Elsevier
Abstract Ethnopharmacological relevance Salvia miltiorrhiza Bunge, a well-known
traditional Chinese medicinal (TCM) plant, has been used to treat cardiovascular diseases …

Tanshinone IIA protects against acetaminophen-induced hepatotoxicity via activating the Nrf2 pathway

W Wang, C Guan, X Sun, Z Zhao, J Li, X Fu, Y Qiu… - Phytomedicine, 2016 - Elsevier
Abstract Background Tanshinone IIA (Tan), the main active component of Salvia miltiorrhiza,
has been demonstrated to have antioxidant activity. Acetaminophen (APAP), a widely used …

In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica

M Fronza, R Murillo, S Ślusarczyk, M Adams… - Bioorganic & medicinal …, 2011 - Elsevier
Phytochemical investigations of the n-hexane extract from the roots of Peltodon longipes
(Lamiaceae) resulted in the isolation of 12 known abietane diterpenes (1–12). Structures …

Algicidal activity of Salvia miltiorrhiza Bung on Microcystis aeruginosa—Towards identification of algicidal substance and determination of inhibition mechanism

C Zhang, YL Yi, K Hao, GL Liu, GX Wang - Chemosphere, 2013 - Elsevier
The present study was to isolate and identify a potent algicidal compound from extract of
Salvia miltiorrhiza and study the potential inhibition mechanism on Microcystis aeruginosa …

Tanshinone derivatives: a patent review (January 2006–September 2012)

XH Tian, JH Wu - Expert Opinion on Therapeutic Patents, 2013 - Taylor & Francis
Introduction: Tanshinone IIA (TSIIA), cryptotanshinone and tanshinone I are major bioactive
constituents of Danshen, a Chinese herbal medicine. Sodium tanshinone IIA sulfonate (STS) …