Diabetic peripheral neuropathy (DPN) occurs in up to half of individuals with type 1 or type 2
diabetes. DPN results from the distal-to-proximal loss of peripheral nerve function, leading to …

Diabetic retinopathy, neuropathy, and nephropathy occur in more than 50% of people with
diabetes, contributing substantially to morbidity and mortality. Patient understanding of these …

Importance Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating adverse
effect of neurotoxic cancer treatments including taxanes and platinum agents. Limited …

Aims/hypothesis The aim of this study was to determine the effect of bariatric surgery on
diabetes complications in individuals with class II/III obesity (BMI> 35 kg/m2). Methods We …

Bariatric surgery in people with obesity can lead to long‐term remission of type 2 diabetes
mellitus (T2DM) and a reduction in the incidence of macrovascular complications. The …

Objective The serum lipidomic profile associated with neuropathy in type 2 diabetes is not
well understood. Obesity and dyslipidemia are known neuropathy risk factors, suggesting …

Background Peripheral neuropathy (PN) is a common complication in obesity, prediabetes,
and type 2 diabetes, though its pathogenesis remains incompletely understood. In a murine …

Recent studies suggest that the accumulation of atypical, 1-deoxysphingolipids that lack the
C1 hydroxyl group may be associated with diabetic neuropathy (DN). We hypothesized that …

Schwann cells (SCs) support peripheral nerves under homeostatic conditions, independent
of myelination, and contribute to damage in prediabetic peripheral neuropathy (PN). Here …

Purpose Chemotherapy-induced peripheral neurotoxicity (CIPN) is a common dose-limiting
toxicity of cancer treatment causing functional impairment and impacting quality of life …