Infection with Mycobacterium tuberculosis causes> 1.5 million deaths worldwide annually.
Innate immune cells are the first to encounter M. tuberculosis, and their response dictates …

Gastrointestinal disease caused by the apicomplexan parasite Cryptosporidium parvum is
one of the most important diseases of young ruminant livestock, particularly neonatal calves …

Most infections with Mycobacterium tuberculosis (Mtb) manifest as a clinically asymptomatic,
contained state, known as latent tuberculosis infection, that affects approximately one …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global
infectious disease and a leading cause of mortality worldwide. Currently, the only available …

Background Tuberculosis (TB) continues to be a critical global health problem, which killed
millions of lives each year. Certain circulating cell subsets are thought to differentially …

The respiratory tract has an approximate surface area of 70 m2 in adult humans, which is in
virtually direct contact with the outside environment. It contains a uniquely rich vascular bed …

Cells of the innate immune system produce cytokines and lipid mediators that strongly
influence the outcome of mycobacterial infection. In the case of Mycobacterium tuberculosis …

Mucosa-associated invariant T (MAIT) cells are a unique population of αβ T cells in
mammals that reside preferentially in mucosal tissues and express an invariant Vα paired …

Natural killer (NK) cells are well recognized for their ability to provide a first line of defence
against viral pathogens and they are increasingly being implicated in immune responses …

Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse
range of pathogens. Recognition of infection by NK cells is accomplished by the activation of …