Biliary Atresia is a devastating pediatric cholangiopathy affecting the bile ducts of the liver. In
this review, we describe recent progress in the understanding of liver development with a …

Cholestatic liver disease denotes any situation associated with impaired bile flow
concomitant with a noxious bile acid accumulation in the liver and/or systemic circulation …

Abstract Background & Aims Tropifexor (TXR) is a novel nonbile acid that acts as an agonist
of farnesoid X receptor (FXR). TXR is currently in Phase 2 trials for the treatment of non …

Aims Liver cirrhosis defines by regenerative nodules and fibrotic septa, causing a
complication called cirrhotic cardiomyopathy (CCM) with chronotropic hypo-responsiveness …

The development of liver fibrosis is one of the most severe and life-threatening outcomes of
chronic liver disease (CLD). For targeted therapy of CLD, it is highly needed to reveal …

Background Biliary obstruction leads to an increase in biliary pressure within the biliary
system, which induces the morphologic adaptation of the biliary tree. Purpose To observe …

Introduction: The common predominant clinical features of cholangiopathies such as primary
sclerosing cholangitis (PSC), primary biliary cholangitis (PBC), and biliary atresia (BA) are …

The present study aimed to develop viable liver organoids using decellularized native liver
scaffolds and evaluate the efficacy of human liver organoid transplantation in a rabbit model …

Background Arterial spin labeling (ASL) has been proven to be effective in ischemia‐
induced acute kidney injury (AKI); however, validation of ASL magnetic resonance imaging …

As a rare complication of liver injury and certain interventions, bile can enter the
bloodstream depending on the pressure gradient, resulting in bilhemia. Its micro-rheological …