Thyroid hormones in critical illness

MJ Maiden, DJ Torpy - Critical care clinics, 2019 - criticalcare.theclinics.com
The thyroid gland produces hormones that primarily regulate cellular metabolism, have wide-
ranging pleiotropic effects, and are essential for life. During critical illness, the most active …

Endocrine changes in brain death and transplantation

AM Ranasinghe, RS Bonser - … practice & research Clinical endocrinology & …, 2011 - Elsevier
Following brain death (BD) many hormonal changes occur. These include an increase and
then a fall in the levels of circulating catecholamines, reduced levels of anti-diuretic hormone …

Low triiodothyronine syndrome as a predictor of poor outcomes in patients undergoing brain tumor surgery: a pilot study

A Bunevicius, V Deltuva, S Tamasauskas… - Journal of …, 2013 - thejns.org
Object A low triiodothyronine (T3) state is highly prevalent and is associated with a poor
prognosis in critically ill patients. The authors investigated, in patients undergoing brain …

The low triiodothyronine syndrome: a strong predictor of low cardiac output and death in patients undergoing coronary artery bypass grafting

AG Cerillo, S Storti, E Kallushi, D Haxhiademi… - The Annals of thoracic …, 2014 - Elsevier
Background There is strong clinical and experimental evidence that altered thyroid
homeostasis negatively affects survival in cardiac patients, but a negative effect of the low …

Thyroid hormone therapy for postoperative nonthyroidal illnesses: a systematic review and synthesis

EM Kaptein, A Sanchez, E Beale… - The Journal of Clinical …, 2010 - academic.oup.com
Context: Effects of thyroid hormone therapy on postoperative morbidity and mortality in
adults remain controversial. Objective: The aim was to conduct a systematic review …

Molecular and biochemical evidences on the protective effects of triiodothyronine against phosphine-induced cardiac and mitochondrial toxicity

AH Abdolghaffari, A Baghaei, R Solgi, M Gooshe… - Life sciences, 2015 - Elsevier
Abstract Aim Aluminum phosphide (AlP) is a widely used fumigant and rodenticide. While
AlP ingestion leads to high mortality, its exact mechanism of action is unclear. There are …

Oral Levothyroxine Prophylactic Administration on Bleeding and Hemoglobin Changes During and after Total Hip Arthroplasty in Patients with a History of Ischemic …

M Zamani Esfahlani, M Irajian… - Trauma …, 2023 - traumamon.com
Introduction: The reduction of thyroid hormones during surgery can affect the amount of
bleeding. This study aimed to evaluate the effects of prophylactic administration of oral …

New insights into mechanisms of cardioprotection mediated by thyroid hormones

G Nicolini, L Pitto, C Kusmic, S Balzan… - Journal of Thyroid …, 2013 - Wiley Online Library
Heart failure represents the final common outcome in cardiovascular diseases. Despite
significant therapeutic advances, morbidity and mortality of heart failure remain …

Cardiovascular protective effects of PPARγ agonists in hypothyroid rats: protection against oxidative stress

Y Baghcheghi, F Beheshti, M Hosseini… - Clinical and …, 2022 - Taylor & Francis
Hypothyroidism disturbs redox homeostasis and takes part in cardiovascular system
dysfunction. Considering antioxidant and cardio-protective effects of PPAR-γ agonists …

[HTML][HTML] Decreased triiodothyronine (T3) as a predictor for prolonged mechanical ventilation in critically ill patients with cardiac surgery

X Shen, J Sun, L Hong, X Song, C Zhang, Y Liu… - BMC …, 2022 - Springer
Background This study aimed to examine the correlation between thyroid hormone and
prolonged mechanical ventilation (MV) in adult critically ill patients having undergone …