[HTML][HTML] Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …
but the solubility parameter cannot compromise, and so different approaches are employed …
[HTML][HTML] Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
[HTML][HTML] Pharmaceutical dispersion techniques for dissolution and bioavailability enhancement of poorly water-soluble drugs
X Zhang, H Xing, Y Zhao, Z Ma - Pharmaceutics, 2018 - mdpi.com
Over the past decades, a large number of drugs as well as drug candidates with poor
dissolution characteristics have been witnessed, which invokes great interest in enabling …
dissolution characteristics have been witnessed, which invokes great interest in enabling …
Formulation strategies to improve the bioavailability of poorly absorbed drugs with special emphasis on self‐emulsifying systems
Poorly water‐soluble drug candidates are becoming more prevalent. It has been estimated
that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous …
that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous …
Self-nanoemulsifying drug delivery systems: formulation insights, applications and advances
AA Date, N Desai, R Dixit, M Nagarsenker - Nanomedicine, 2010 - Taylor & Francis
There has been a resurgence of interest in nanoemulsions for various pharmaceutical
applications since low-energy emulsification methods, such as spontaneous or self …
applications since low-energy emulsification methods, such as spontaneous or self …
Self nanoemulsifying drug delivery system (SNEDDS) of rosuvastatin calcium: design, formulation, bioavailability and pharmacokinetic evaluation
K Balakumar, CV Raghavan, S Abdu - Colloids and Surfaces B …, 2013 - Elsevier
The aim of the present study is to improve solubility and bioavailability of Rosuvastatin
calcium using self nanoemulsifying drug delivery system (SNEDDS). Self emulsifying …
calcium using self nanoemulsifying drug delivery system (SNEDDS). Self emulsifying …
New perspectives on lipid and surfactant based drug delivery systems for oral delivery of poorly soluble drugs
A Müllertz, A Ogbonna, S Ren… - Journal of pharmacy and …, 2010 - academic.oup.com
Objectives The aim of this review is to highlight relevant considerations when implementing
a rational strategy for the development of lipid and surfactant based drug delivery system …
a rational strategy for the development of lipid and surfactant based drug delivery system …
SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: development and optimization
The aim of this study was to develop and optimize SNEDDS formulations containing
surfactants reported to be bioenhancers for improvement of dissolution and oral absorption …
surfactants reported to be bioenhancers for improvement of dissolution and oral absorption …
[HTML][HTML] Novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for oral delivery of olmesartan medoxomil: design, formulation, pharmacokinetic and …
The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution …
system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution …
[HTML][HTML] Impact of process parameters in the generation of novel aspirin nanoemulsions–comparative studies between ultrasound cavitation and microfluidizer
SY Tang, P Shridharan, M Sivakumar - Ultrasonics sonochemistry, 2013 - Elsevier
In the present investigation, the operating efficiency of a bench-top air-driven microfluidizer
has been compared to that of a bench-top high power ultrasound horn in the production of …
has been compared to that of a bench-top high power ultrasound horn in the production of …